IONIS PHARMACEUTICALS INC
IONSAbout the company
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA).
Investment snapshot
Positive
3
BUY / PASS
Neutral / negative
1 / 12
NEUTRAL / FAIL
Median fair value
—
No comparable estimates
Models with upside
0 / 17
Positive margin of safety
Strongest signal
9 of 12 pass — Buffett, Lynch and Marks object
Key risk
No clean pass — all 13 investors flag at least one valuation criterion
Framework analysis
| Verdict | Meaning |
|---|---|
| BUY | Positive purchase signal: the framework's buy requirements are met. |
| PASS | The company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state. |
| NEUTRAL | Neither a positive nor negative conclusion. It does not mean to hold an existing position. |
| FAIL | The company does not clear the framework's requirements. |
| Ranked | Ranked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL. |
Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.
| Metric | Graham Defensive Value | Buffett Quality Compounder | Lynch GARP | Greenblatt Magic Formula | Piotroski F-Score | Dreman Contrarian Value | Munger Quality Focus | Pabrai Dhandho Framework | Akre Three-Legged Stool | Marks Risk-Aware Value | Ackman Activist Value | Templeton Global Bargain Hunter | Sleep Scale Economies Shared | Asness Systematic Factors | Neff Low-P/E Total Return | Schloss Asset-Value Discipline | O'Shaughnessy Systematic Factor Composite |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Verdict | FAIL | FAIL | FAIL | FAIL · Rank #2106 (Top 68%) | PASS | FAIL | FAIL | FAIL | FAIL | FAIL | PASS | PASS | FAIL | FAIL | FAIL | FAIL | NEUTRAL |
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| Analysis | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… |
| Intrinsic Value (annual) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Margin of Safety | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Financial Basis | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Annual history · FY 2025 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 · TTM ended 2026-09-30 vs 2025-09-30 · TTM ended 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-02-26 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Price history 2025-01-01–2026-11-01 · Annual history · FY 2025 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-09 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 Latest source filing: 2026-11-09 Score computed: 2026-11-14 |
Where It Passes
- Debt & Leverage75% pass✓ 12✗ 3▾
9 of 12 pass — Buffett, Lynch and Marks object
LT Debt vs Net Current AssetsLT Debt $1.3B vs NCA $2.2B✓GrahamLT Debt <= Net Current AssetsDebt/Equity & Interest CoverageD/E: 0.00, IC: -29.4x✗BuffettD/E < 0.5 AND Interest Coverage > 5xTotal Debt / Equity0✓Lynch< 0.33Cash - Long-term Debt$-955.7M✗LynchPositive preferredLT Debt / Total Assets Change40.03% -> 37.69%✓PiotroskiDecreased YoYCurrent Assets / Current Liabilities5.43✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)Total Debt / Shareholders' Equity0✓Dreman< 0.8✓Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✓SchlossD/E < 1.00xDebt Levels0✓MungerDebt/Equity < 0.5✓AkreDebt/Equity < 0.3Interest Coverage & Debt/EBITDAIC=-22.1x, D/EBITDA=N/A (D&A unavailable)✗MarksInterest Coverage > 3x; Debt/EBITDA < 4xTotal Debt / Shareholders Equity0✓Ackman<= 1.0Negative debt-to-equity (higher means less debt)-0.0000; #1/4210 (top 0.0%)✓AsnessTop 30% of eligible cross-section
Where It Falls Short
- Valuation0% pass✓ 1✗ 27▾
No clean pass — all 13 investors flag at least one valuation criterion
Price / 3-yr avg EPS✗Graham<= 15xPrice-to-Book Ratio9.8x✗Graham<= 1.5xP/E x P/B✗Graham<= 22.5Basic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)EBIT / Enterprise Value-6.1%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-6.1%, ROC=-16.0%✗GreenblattBoth EY > 10% and ROC > 25%Price / EPS✗Dreman< 12x✗Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)Price / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xPrice / Book Value per Share9.8x✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)Valuation Reasonableness✗MungerP/E < 25 or Owner Earnings Yield > 5%P/E or FCF YieldFCF Yield=-6.6%✗PabraiP/E < 15 or FCF Yield > 10%P/B or P/E vs. Historical AverageP/B=9.8x✗MarksP/E < 15 or P/B < 2.0Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePrice / FCF per ShareN/A (negative FCF)✗Ackman<= 25Price vs. Trailing Low100% of trailing low ($29.06)✓Templeton<= 120% of trailing low (certified split-adjusted live window)Net income / market capitalization-11.29%; #4234/6340 (top 66.8%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionPositive book equity / market capitalization+0.0813; #4852/6449 (top 75.2%)✗AsnessTop 30% of eligible cross-sectionPrice / Diluted EPS✗NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)(EPS CAGR % + Dividend Yield %) / P/E✗Neff> 0.7 (Neff's published traditional edge)Price / Tangible Book Value per Share9.82x✗SchlossP/TBV <= 1.00x (app cutoff)Book Value per Share Change-43.9%✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)Revenue / market capitalization+0.1984; #3796/5247 (top 72.3%)✗OshaughnessyTop 10% of eligible cross-section(Operating cash flow - capex) / market capitalization-12.73%; #3328/4519 (top 73.6%)✗OshaughnessyTop 10% of eligible cross-sectionTrailing six-month price return through the evaluation date-61.34%; #5431/6202 (top 87.6%)✗OshaughnessyTop 10% of eligible cross-section - Cash Flow0% pass✓ 1✗ 11▾
No clean pass — all 10 investors flag at least one cash flow criterion
Free Cash Flow Proxy✗BuffettPositive and growingFCF Positive and Growing$-616.3M✗LynchPositive and growingOperating Cash Flow$-268.6M✗PiotroskiCFO > 0(CFO / Total Assets) vs ROACFO/Assets=-7.62%, ROA=-10.82%✓PiotroskiCFO/Assets > ROAPrice / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xP/E or FCF YieldFCF Yield=-6.6%✗PabraiP/E < 15 or FCF Yield > 10%FCF Positive9/18 years FCF positive✗MarksPositive FCF in majority of recent years(OCF - CapEx) / Market Cap-12.8%✗Ackman>= 4%Price / FCF per ShareN/A (negative FCF)✗Ackman<= 25Positive Operating Cash Flow frequency10/18 years positive✗SleepPositive OCF in >= 70% of available yearsOperating Cash Flow - Capital Expenditures$-616.3M✗Neff> $0 (app proxy for a strong fundamental case)(Operating cash flow - capex) / market capitalization-12.73%; #3328/4519 (top 73.6%)✗OshaughnessyTop 10% of eligible cross-section - Growth0% pass✓ 2✗ 11▾
No clean pass — all 8 investors flag at least one growth criterion
EPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passInventory Growth vs Revenue GrowthInv: 173.0% vs Rev: -0.7%✗LynchInventory growth < Revenue growthEPS Growth Direction$-0.19 (2008) -> $-2.38 (2025)✗DremanPositive over recent yearsEPS CAGR2.8% CAGR over 10 years✗Dreman> 5% annualizedPositive Net Income Frequency4/18 years positive✗MarksPositive net income in >= 7 of last 10 years3yr Median Revenue Growth33.8%✓Ackman>= 5%Positive EPS Growth Frequency2/5 years with positive EPS growth✗AckmanPositive EPS growth in >= 3 of last 5 years5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Revenue growth vs. gross and operating margin trendgross margin 98.8% -> 98.3%, operating margin -44.9% -> -40.4%✓SleepRevenue rising; gross margin flat or falling; operating margin holding5-year Revenue CAGR5.3%✗SleepCAGR > 7%3-5 Year Diluted EPS CAGR✗Neff7%-20% annualized - Profitability6% pass✓ 5✗ 30▾
15 of 16 flag IONS's profitability — Graham, Buffett, Lynch +12 more
Positive EPS (10 years)4/28 years positive✗GrahamPositive EPS every year for 10 yearsEPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthNet Income Positive (10+ years)4/28 years positive✗BuffettPositive every year for 10+ yearsROE (up to 5-year arithmetic mean)-60.1%✗Buffett> 15% arithmetic mean (app rule)Operating Margin (10-yr trend)-40.4% (latest)✓BuffettStable or rising over 10 yearsFree Cash Flow Proxy✗BuffettPositive and growingEarnings Variance (10-yr CoV)N/A (negative mean EPS)✗BuffettCoV < 0.3Retained Earnings Effectiveness✗Buffett$1 retained -> > $1 market value createdBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passROE-138.8%✗Lynch> 15%EBIT / Enterprise Value-6.1%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-6.1%, ROC=-16.0%✗GreenblattBoth EY > 10% and ROC > 25%Net Income / Total Assets-10.82%✗PiotroskiROA > 0ROA Change YoY-15.11% -> -10.82% (delta: +4.29%)✓PiotroskiCurrent ROA > Prior ROA(CFO / Total Assets) vs ROACFO/Assets=-7.62%, ROA=-10.82%✓PiotroskiCFO/Assets > ROAGross Margin Change YoY98.4% -> 98.3%✗PiotroskiImproved YoYPre-Tax Income / Revenue-56.6%✗Dreman>= 8%Net Income / Shareholders' Equity-138.8%✗Dreman> 12%Margin of SafetyP/B=9.8x✗PabraiP/B < 1.5 or P/E < 15Return on Equity-83.3% (3-yr avg)✗AkreROE > 20% (3-year avg)Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePositive Net Income Frequency4/18 years positive✗MarksPositive net income in >= 7 of last 10 yearsOperating Income / Revenue-58.8%✗Ackman>= 15%Net Income / Shareholders Equity-138.8%✗Ackman>= 15%5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Operating Margin Trend-44.9% (2023) -> -40.4% (2025)✓TempletonNon-negative operating-margin trend over 3 yearsRevenue growth vs. gross and operating margin trendgross margin 98.8% -> 98.3%, operating margin -44.9% -> -40.4%✓SleepRevenue rising; gross margin flat or falling; operating margin holdingNet income / market capitalization-11.29%; #4234/6340 (top 66.8%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionGross profit / total assets+26.33%; #1634/3702 (top 44.1%)✗AsnessTop 30% of eligible cross-sectionNet income / positive book equity-138.84%; #4748/5226 (top 90.9%)✗AsnessTop 30% of eligible cross-sectionNegative 5-year standard deviation of ROA-0.0472; #2511/5884 (top 42.7%)✗AsnessTop 30% of eligible cross-section3-5 Year Diluted EPS CAGR✗Neff7%-20% annualizedPositive Diluted-EPS Years3/10 years positive✗Schloss>= 70% positive over 5-10 observed years (app rule) - Verdicts19% pass✓ 3✗ 13▾
Split decision: 12 FAIL · 3 PASS · 1 NEUTRAL
Overall verdict✗GrahamFAIL (3/9)✗BuffettFAIL (1/9)✗LynchFAIL (1/7)✗GreenblattRank #2106✓PiotroskiPASS (F-Score 4)✗DremanFAIL (3/11)✗MungerFAIL (1/4)✗PabraiFAIL (0/3)✗AkreFAIL (2/6)✗MarksFAIL (0/5)✓AckmanPASS (4/9)✓TempletonPASS (4/8)✗SleepFAIL (2/6)✗AsnessFAIL (Rank #1943/2370 (Top 82.0%))✗NeffFAIL (1/6)✗SchlossFAIL (2/7)•OshaughnessyNEUTRAL (Not ranked) - Efficiency25% pass✓ 3✗ 8▾
6 of 8 flag IONS's efficiency — Buffett, Greenblatt, Piotroski +3 more
Current Ratio5.43✓Graham>= 2.0ROIC (3-5 yr avg)-19.3%✗Buffett> 10%ROIC - WACC-29.3%✗BuffettPositive (WACC = 10%)EBIT / (NWC + Net Fixed Assets)-16.0%✗Greenblatt> 25%Current Ratio Change YoY8.47 -> 3.83✗PiotroskiIncreased YoYRevenue / Total Assets Change YoY0.23x -> 0.27x✓PiotroskiImproved YoYCurrent Assets / Current Liabilities5.43✓Dreman> 1.5Return on Invested Capital-113.4%✗Munger> 15%ROIC (high and growing)FY2023: ROIC=-17.2%; FY2024: ROIC=-21.0%; FY2025: ROIC=-13.4%✗AkreLatest 3 consecutive FYs: ROIC > 15% in eachReinvestment Rate x ROICN/A (non-positive net income)✗AkreReinvestment Rate * ROIC > 10%ROIC (5-year)0/4 years above 12% (latest -13.4%)✗SleepROIC > 12% in a majority of years
Business & financials
Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.
Company Profile
Financial Snapshot
Shareholder Return
Fiscal 2025
Issued 3.9% of shares last year, 13.3% issued over two.
- Buybacks
- —
- Dividends
- —
Company Financials
Latest TTM and quarters alongside annual years
TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.
The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.
| Metric | TTM · 2026-09-30 2025-10-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: pre tax income, interest expense, operating cash flow, capex. | Q3 FY 2026 2026-07-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, capex. | Q2 FY 2026 2026-04-01 – 2026-06-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, capex. | Q1 FY 2026 2026-01-01 – 2026-03-31 Sources | FY 2025Sources
| FY 2024Sources
| FY 2023Sources
| FY 2022Sources
| FY 2021Sources
|
|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $4.8Bcurrent | -- | -- | -- | $13.7Best. | $5.1Best. | $7.5Best. | $5.7Best. | $4.5Best. |
| Revenue | $960.1M↓1% | $242.7M↑55% | $267.9M↓41% | $246.1M↑87% | $943.7M↑34% | $705.1M↓10% | $787.6M↑34% | $587.4M↓28% | $810.5M |
| Operating Income | -$564.9M↓103% | -$130.7M↑18% | -$102.3M↓173% | -$117.4M↑20% | -$381.7M↑20% | -$475.1M↓34% | -$353.7M↑14% | -$410.2M↓1259% | -$30.2M |
| Net Income | -$546.5M↓113% | -$110.0M↑14% | -$114.6M↓193% | -$92.5M↑37% | -$381.4M↑16% | -$453.9M↓24% | -$366.3M↓36% | -$269.7M↓843% | -$28.6M |
| EPS (Diluted) | -- | $-0.66↑18% | $-0.69↓199% | $-0.56↑40% | $-2.38↑22% | $-3.04↓19% | $-2.56↓35% | $-1.90↓850% | $-0.20 |
| Gross Margin | — | — | — | — | 98.3% | 98.4% | 98.8%↑1% | 97.6%↓1% | 98.7% |
| Operating Margin | -58.8%↓105% | -53.8%↑47% | -38.2%↓223% | -47.7%↑57% | -40.4%↑40% | -67.4%↓50% | -44.9%↑36% | -69.8%↓1775% | -3.7% |
| ROE | -138.8%↓235% | — | — | — | -78.0%↓1% | -77.1%↑19% | -94.7%↓101% | -47.1%↓1171% | -3.7% |
| Total Debt | $0↓100% | $0↓100% | $0↓100% | $432.5M | $1.8B↑46% | $1.2B↓3% | $1.2B↑6% | $1.2B | -- |
| Shareholders' Equity | $393.6M↓36% | $393.6M↓36% | $439.7M↓30% | $491.4M↑3% | $489.1M↓17% | $588.4M↑52% | $386.7M↓33% | $572.9M↓26% | $771.7M |
| Current Ratio | 5.43↑95% | 5.43↑95% | 7.89↑175% | 4.10↓58% | 3.83↓55% | 8.47↑44% | 5.90↓17% | 7.07↓27% | 9.75 |
| Debt / Equity | 0.00↓100% | 0.00↓100% | 0.00↓100% | 0.88 | 3.60↑76% | 2.04↓36% | 3.21↑56% | 2.05 | — |
| Operating Cash Flow | -$544.4M↓120% | -$179.4M↓37% | $565.5M↑274% | -$792.8M↓426% | -$268.6M↑46% | -$500.9M↓63% | -$307.5M↓12% | -$274.4M↓991% | $30.8M |
| Free Cash Flow | -$616.3M↓104% | -$192.1M↓41% | $549.5M↑295% | -$814.6M↓399% | -$320.0M↑41% | -$546.2M↓65% | -$331.3M↓14% | -$290.1M↓1639% | $18.8M |
Score history
Historical Score Timeline
Industry peers
Industry Peers
Similar companies in Pharmaceutical Products
IONS vs Peers — Financial Grading
| Company | Market Cap | Price | Revenue | Net Income | ROE | D/E | Op. Margin | Curr. Ratio | Graham | Buffett | Lynch | Greenblatt | Piotroski | Dreman |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck & Co., Inc.MRK | $364.3B | $147.76 | $65.0B | $18.3B | 34.7% | 0.94 | — | 1.54 | 2/9 | 5/9 | 4/7 | 0/3 | F-Score 4 | 1/11 |
| ABBOTT LABORATORIESABT | $188.0B | $108.52 | $44.3B | $6.5B | 12.5% | 0.25 | 18.2% | 1.58 | 3/9 | 4/9 | 2/7 | 1/3 | F-Score 5 | 3/11 |
| BRISTOL MYERS SQUIBB COBMY | $129.7B | $63.43 | $48.2B | $7.1B | 38.2% | 2.44 | 19.4% | 1.26 | 2/9 | 1/9 | 3/7 | 1/3 | F-Score 8 | 5/11 |
| BIO-TECHNE CorpTECH | $11.4B | $72.80 | $1.2B | $73.4M | 3.8% | — | 8.4% | 3.46 | 4/9 | 3/9 | 3/7 | 0/3 | F-Score 5 | 4/11 |
| REPLIGEN CORPRGEN | $10.7B | $167.79 | $738.3M | $48.9M | 2.3% | 0.26 | 7.5% | 8.37 | 3/9 | 2/9 | 3/7 | 0/3 | F-Score 7 | 5/11 |
| NEOGEN CORPNEOG | $2.5B | $11.23 | $870.4M | $7.9M | -0.4% | 0.76 | -2.5% | 3.82 | 3/9 | 1/9 | 2/7 | 0/3 | F-Score 6 | 4/11 |
| Pharvaris N.V.PHVS | $2.4B | $33.36 | — | $206.4M | -64.8% | 0.00 | — | — | 0/9 | 0/9 | 2/7 | 0/3 | F-Score 2 | 2/11 |
| Celldex Therapeutics, Inc.CLDX | $2.3B | $28.83 | $1.5M | $258.8M | -49.1% | — | -18599.8% | 10.49 | 1/9 | 0/9 | 1/7 | 0/3 | F-Score 2 | 2/11 |