Chemomab Therapeutics Ltd.

CMMB
About the company

Chemomab Therapeutics Ltd., a clinical-stage biotechnology company, focuses on the discovery and development of therapeutics for the treatment of fibrotic and inflammatory diseases. Its lead product candidate is nebokitug, a humanized monoclonal antibody that attenuates the basic function of CCL24 as a regulator of major inflammatory and fibrotic pathways, which has completed phase 2 clinical trial for treating primary sclerosing cholangitis, as well as in phase 2 clinical trial to treat systemic sclerosis. The company was founded in 2011 and is based in Tel Aviv-Yafo, Israel.

Country: IsraelPrice: $1.53Market Cap: $12.3M

Investment snapshot

0%positive consensus
Scored 1d ago

Positive

0

BUY / PASS

Neutral / negative

2 / 14

NEUTRAL / FAIL

Median fair value

$1.02

-33.3% vs price

Models with upside

1 / 17

Positive margin of safety

Key risk

No clean pass — all 13 investors flag at least one valuation criterion

Framework analysis

VerdictMeaning
BUYPositive purchase signal: the framework's buy requirements are met.
PASSThe company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state.
NEUTRALNeither a positive nor negative conclusion. It does not mean to hold an existing position.
FAILThe company does not clear the framework's requirements.
RankedRanked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL.

Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.

MetricGraham

Defensive Value

Buffett

Quality Compounder

Lynch

GARP

Greenblatt

Magic Formula

Piotroski

F-Score

Dreman

Contrarian Value

Munger

Quality Focus

Pabrai

Dhandho Framework

Akre

Three-Legged Stool

Marks

Risk-Aware Value

Ackman

Activist Value

Templeton

Global Bargain Hunter

Sleep

Scale Economies Shared

Asness

Systematic Factors

Neff

Low-P/E Total Return

Schloss

Asset-Value Discipline

O'Shaughnessy

Systematic Factor Composite

VerdictFAILFAILFAILFAIL · Rank #3096 (Top 100%)FAILFAILFAILFAILFAILFAILFAILFAILFAILNEUTRALFAILFAILNEUTRAL
Score
AnalysisChecking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…
Intrinsic Value (annual)N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Margin of SafetyN/AN/AN/AN/AN/A-91.2%N/AN/AN/A+77.3%N/A-50.0%N/AN/AN/AN/AN/A
Financial Basis

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Market data at 2026-11-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Market data at 2026-11-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Price history 2025-01-01–2026-11-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Price history 2025-01-01–2026-11-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Price history 2025-01-01–2026-11-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Where It Passes

    Where It Falls Short

    • Valuation0% pass✓ 1✗ 27▾

      No clean pass — all 13 investors flag at least one valuation criterion

      Price / 3-yr avg EPS28.7x
      ✗Graham<= 15x
      Price-to-Book Ratio
      ✗Graham<= 1.5x
      P/E x P/B
      ✗Graham<= 22.5
      Basic earnings-growth PEG (dividends excluded)P/E 85.0x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      EBIT / Enterprise Value-2357.7%
      ✗Greenblatt> 10%
      Earnings Yield + ROC AssessmentEY=-2357.7%, ROC=-2456.7%
      ✗GreenblattBoth EY > 10% and ROC > 25%
      Price / EPS85.0x
      ✗Dreman< 12x✗Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)
      Price / (CFO / Shares)
      ✗Dreman< 8x
      Price / Book Value per Share
      ✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)
      Valuation ReasonablenessP/E=85.0x
      ✗MungerP/E < 25 or Owner Earnings Yield > 5%
      P/E or FCF YieldP/E=85.0x, FCF Yield=-90.4%
      ✗PabraiP/E < 15 or FCF Yield > 10%
      P/B or P/E vs. Historical AverageP/E=85.0x
      ✗MarksP/E < 15 or P/B < 2.0
      Discount to Intrinsic Value-91.2% (IV=$0.80 vs Price=$1.53)
      ✗Marks>= 20% below intrinsic value
      Price / FCF per Share
      ✗Ackman<= 25
      Price vs. Trailing Low132% of trailing low ($1.16)
      ✗Templeton<= 120% of trailing low (certified split-adjusted live window)
      Net income / market capitalization-73.04%; #5241/6340 (top 82.7%)
      ✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-section
      Positive book equity / market capitalization+1.0016; #1487/6449 (top 23.1%)
      ✓AsnessTop 30% of eligible cross-section
      Price / Diluted EPS85.0x
      ✗NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)
      (EPS CAGR % + Dividend Yield %) / P/E
      ✗Neff> 0.7 (Neff's published traditional edge)
      Price / Tangible Book Value per Share
      ✗SchlossP/TBV <= 1.00x (app cutoff)
      Book Value per Share Change
      ✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)
      Revenue / market capitalization
      ✗OshaughnessyTop 10% of eligible cross-section
      (Operating cash flow - capex) / market capitalization-90.41%; #4039/4519 (top 89.4%)
      ✗OshaughnessyTop 10% of eligible cross-section
      Trailing six-month price return through the evaluation date-8.38%; #3336/6202 (top 53.8%)
      ✗OshaughnessyTop 10% of eligible cross-section
    • Cash Flow0% pass✗ 12▾

      All 10 investors flag CMMB's cash flow

      Free Cash Flow Proxy
      ✗BuffettPositive and growing
      FCF Positive and Growing$-11.1M
      ✗LynchPositive and growing
      Operating Cash Flow$-11.1M
      ✗PiotroskiCFO > 0
      (CFO / Total Assets) vs ROACFO/Assets=-80.58%, ROA=-65.12%
      ✗PiotroskiCFO/Assets > ROA
      Price / (CFO / Shares)
      ✗Dreman< 8x
      P/E or FCF YieldP/E=85.0x, FCF Yield=-90.4%
      ✗PabraiP/E < 15 or FCF Yield > 10%
      FCF Positive0/10 years FCF positive
      ✗MarksPositive FCF in majority of recent years
      (OCF - CapEx) / Market Cap
      ✗Ackman>= 4%
      Price / FCF per Share
      ✗Ackman<= 25
      Positive Operating Cash Flow frequency0/10 years positive
      ✗SleepPositive OCF in >= 70% of available years
      Operating Cash Flow - Capital Expenditures$-11.1M
      ✗Neff> $0 (app proxy for a strong fundamental case)
      (Operating cash flow - capex) / market capitalization-90.41%; #4039/4519 (top 89.4%)
      ✗OshaughnessyTop 10% of eligible cross-section
    • Growth0% pass✓ 1✗ 12▾

      No clean pass — all 8 investors flag at least one growth criterion

      EPS Growth (3-yr avg, 10-yr window)-94.6%
      ✗Graham>= 33% growth
      Basic earnings-growth PEG (dividends excluded)P/E 85.0x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      3-5 Year EPS CAGR-43.4%
      ✗Lynch15-30% (Fast Grower); > 0% to pass
      Inventory Growth vs Revenue GrowthN/A (no inventory)
      ✓LynchInventory growth < Revenue growth
      EPS Growth Direction$0.87 (2016) -> $0.02 (2025)
      ✗DremanPositive over recent years
      EPS CAGR-35.0% CAGR over 9 years
      ✗Dreman> 5% annualized
      Positive Net Income Frequency0/10 years positive
      ✗MarksPositive net income in >= 7 of last 10 years
      3yr Median Revenue Growth
      ✗Ackman>= 5%
      Positive EPS Growth Frequency1/5 years with positive EPS growth
      ✗AckmanPositive EPS growth in >= 3 of last 5 years
      5-Year EPS CAGR-43.4% CAGR over 5 years
      ✗Templeton> 0% (5-year EPS CAGR)
      Revenue growth vs. gross and operating margin trend
      ✗SleepRevenue rising; gross margin flat or falling; operating margin holding
      5-year Revenue CAGR
      ✗SleepCAGR > 7%
      3-5 Year Diluted EPS CAGR-43.4% over 5 years
      ✗Neff7%-20% annualized
    • Verdicts0% pass✗ 15▾

      Split decision: 14 FAIL · 2 NEUTRAL

      Overall verdict
      ✗GrahamFAIL (1/9)✗BuffettFAIL (0/9)✗LynchFAIL (1/7)✗GreenblattRank #3096✗PiotroskiFAIL (F-Score 3)✗DremanFAIL (1/11)✗MungerFAIL (1/4)✗PabraiFAIL (0/3)✗AkreFAIL (0/6)✗MarksFAIL (0/5)✗AckmanFAIL (0/9)✗TempletonFAIL (1/8)✗SleepFAIL (0/6)•AsnessNEUTRAL (Not ranked)✗NeffFAIL (0/6)✗SchlossFAIL (2/7)•OshaughnessyNEUTRAL (Not ranked)
    • Profitability6% pass✓ 2✗ 33▾

      15 of 16 flag CMMB's profitability — Graham, Buffett, Lynch +12 more

      Positive EPS (10 years)10/11 years positive
      ✗GrahamPositive EPS every year for 10 years
      EPS Growth (3-yr avg, 10-yr window)-94.6%
      ✗Graham>= 33% growth
      Net Income Positive (10+ years)0/11 years positive
      ✗BuffettPositive every year for 10+ years
      ROE (up to 5-year arithmetic mean)-83.0%
      ✗Buffett> 15% arithmetic mean (app rule)
      Operating Margin (10-yr trend)
      ✗BuffettStable or rising over 10 years
      Free Cash Flow Proxy
      ✗BuffettPositive and growing
      Earnings Variance (10-yr CoV)0.96
      ✗BuffettCoV < 0.3
      Retained Earnings Effectiveness
      ✗Buffett$1 retained -> > $1 market value created
      Basic earnings-growth PEG (dividends excluded)P/E 85.0x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      3-5 Year EPS CAGR-43.4%
      ✗Lynch15-30% (Fast Grower); > 0% to pass
      ROE-72.9%
      ✗Lynch> 15%
      EBIT / Enterprise Value-2357.7%
      ✗Greenblatt> 10%
      Earnings Yield + ROC AssessmentEY=-2357.7%, ROC=-2456.7%
      ✗GreenblattBoth EY > 10% and ROC > 25%
      Net Income / Total Assets-65.12%
      ✗PiotroskiROA > 0
      ROA Change YoY-82.20% -> -65.12% (delta: +17.08%)
      ✓PiotroskiCurrent ROA > Prior ROA
      (CFO / Total Assets) vs ROACFO/Assets=-80.58%, ROA=-65.12%
      ✗PiotroskiCFO/Assets > ROA
      Gross Margin Change YoY
      ✗PiotroskiImproved YoY
      Pre-Tax Income / Revenue
      ✗Dreman>= 8%
      Net Income / Shareholders' Equity-72.9%
      ✗Dreman> 12%
      Margin of SafetyP/E=85.0x
      ✗PabraiP/B < 1.5 or P/E < 15
      Return on Equity-106.1% (3-yr avg)
      ✗AkreROE > 20% (3-year avg)
      Discount to Intrinsic Value-91.2% (IV=$0.80 vs Price=$1.53)
      ✗Marks>= 20% below intrinsic value
      Positive Net Income Frequency0/10 years positive
      ✗MarksPositive net income in >= 7 of last 10 years
      Operating Income / Revenue
      ✗Ackman>= 15%
      Net Income / Shareholders Equity-72.9%
      ✗Ackman>= 15%
      5-Year EPS CAGR-43.4% CAGR over 5 years
      ✗Templeton> 0% (5-year EPS CAGR)
      Operating Margin Trend
      ✗TempletonNon-negative operating-margin trend over 3 years
      Revenue growth vs. gross and operating margin trend
      ✗SleepRevenue rising; gross margin flat or falling; operating margin holding
      Net income / market capitalization-73.04%; #5241/6340 (top 82.7%)
      ✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-section
      Gross profit / total assets
      ✗AsnessTop 30% of eligible cross-section
      Net income / positive book equity-72.93%; #4428/5226 (top 84.7%)
      ✗AsnessTop 30% of eligible cross-section
      Negative 5-year standard deviation of ROA-0.2931; #4583/5884 (top 77.9%)
      ✗AsnessTop 30% of eligible cross-section
      3-5 Year Diluted EPS CAGR-43.4% over 5 years
      ✗Neff7%-20% annualized
      Positive Diluted-EPS Years10/10 years positive
      ✓Schloss>= 70% positive over 5-10 observed years (app rule)
    • Debt & Leverage8% pass✓ 3✗ 12▾

      11 of 12 flag CMMB's debt & leverage — Graham, Buffett, Lynch +8 more

      LT Debt vs Net Current Assets
      ✗GrahamLT Debt <= Net Current Assets
      Debt/Equity & Interest Coverage
      ✗BuffettD/E < 0.5 AND Interest Coverage > 5x
      Total Debt / Equity
      ✗Lynch< 0.33
      Cash - Long-term Debt
      ✗LynchPositive preferred
      LT Debt / Total Assets Change0.00% -> 0.00%
      ✓PiotroskiDecreased YoY
      Current Assets / Current Liabilities9.08
      ✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)
      Total Debt / Shareholders' Equity
      ✗Dreman< 0.8✗Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✗SchlossD/E < 1.00x
      Debt Levels
      ✗MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3
      Interest Coverage & Debt/EBITDA
      ✗MarksInterest Coverage > 3x; Debt/EBITDA < 4x
      Total Debt / Shareholders Equity
      ✗Ackman<= 1.0
      Negative debt-to-equity (higher means less debt)
      ✗AsnessTop 30% of eligible cross-section
    • Efficiency25% pass✓ 3✗ 8▾

      6 of 8 flag CMMB's efficiency — Buffett, Greenblatt, Piotroski +3 more

      Current Ratio9.08
      ✓Graham>= 2.0
      ROIC (3-5 yr avg)-258.4%
      ✗Buffett> 10%
      ROIC - WACC-268.4%
      ✗BuffettPositive (WACC = 10%)
      EBIT / (NWC + Net Fixed Assets)-2456.7%
      ✗Greenblatt> 25%
      Current Ratio Change YoY4.98 -> 9.08
      ✓PiotroskiIncreased YoY
      Revenue / Total Assets Change YoY
      ✗PiotroskiImproved YoY
      Current Assets / Current Liabilities9.08
      ✓Dreman> 1.5
      Return on Invested Capital
      ✗Munger> 15%
      ROIC (high and growing)FY2023: ROIC=unavailable; FY2024: ROIC=unavailable; FY2025: ROIC=unavailable
      ✗AkreLatest 3 consecutive FYs: ROIC > 15% in each
      Reinvestment Rate x ROIC
      ✗AkreReinvestment Rate * ROIC > 10%
      ROIC (5-year)
      ✗SleepROIC > 12% in a majority of years
    • Valuation models33% pass✓ 1✗ 2▾

      Models split on CMMB at $1.53 — fair values range $0.80–$6.74

      Dreman fair value$0.80
      ✗Dreman-91.2% margin vs $1.53
      Marks fair value$6.74
      ✓Marks+77.3% margin vs $1.53
      Templeton fair value$1.02
      ✗Templeton-50.0% margin vs $1.53

    Business & financials

    Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.

    Company Profile

    Industry: Pharmaceutical Products
    SIC Sector: Chemicals & Pharmaceuticals
    Size: Micro Cap($12.3M)
    Revenue: N/A
    Net Income: $9.0M+35.5% YoY

    Financial Snapshot

    Operating Margin--
    Return on Equity-72.9%
    Debt / Equity--
    Current Ratio9.08
    EPS (Diluted)$0.02

    Company Financials

    Latest TTM and quarters alongside annual years

    TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.

    MetricFY 2025
    Sources
    • 20-F · 2026-03-23
    FY 2024
    Sources
    • 20-F · 2025-04-04
    FY 2023
    Sources
    • 20-F · 2024-03-28
    FY 2022
    Sources
    • 10-K · 2023-03-20
    FY 2021
    Sources
    • 10-K · 2022-03-30
    Market Cap$12.3Mcurrent--------
    Revenue----------
    Operating Income-$112.0M↓9%-$103.0M------
    Net Income-$9.0M↑35%-$13.9M↑42%-$24.2M↑12%-$27.6M↓122%-$12.5M
    EPS (Diluted)$0.02↓54%$0.04↓62%$0.10↓15%$0.12↑102%$0.06
    Gross Margin—————
    Operating Margin—————
    ROE-72.9%↑29%-103.0%↑28%-142.5%↓87%-76.3%↓276%-20.3%
    Total Debt----------
    Shareholders' Equity$12.3M↓9%$13.5M↓20%$17.0M↓53%$36.2M↓41%$61.5M
    Current Ratio9.08↑82%4.98↑15%4.32↓30%6.18↓74%23.66
    Debt / Equity—————
    Operating Cash Flow-$11.1M↑28%-$15.4M↑35%-$23.6M↓16%-$20.4M↓65%-$12.4M
    Free Cash Flow-$11.1M↑28%-$15.4M↑35%-$23.6M↓16%-$20.4M↓62%-$12.6M

    Score history

    Historical Score Timeline

    Industry peers

    Industry Peers

    Similar companies in Pharmaceutical Products

    CMMB vs Peers — Financial Grading

    RevenueN/A
    Net Income$9.0MBottom 25%
    ROE-72.9%Bottom 25%
    D/E—
    Op. Margin—
    Curr. Ratio9.08Top 25%
    CompanyMarket CapPriceRevenueNet IncomeROED/EOp. MarginCurr. RatioGrahamBuffettLynchGreenblattPiotroskiDreman
    Merck & Co., Inc.MRK$364.3B$147.76$65.0B$18.3B34.7%0.94—1.542/95/94/70/3F-Score 41/11
    ABBOTT LABORATORIESABT$188.0B$108.52$44.3B$6.5B12.5%0.2518.2%1.583/94/92/71/3F-Score 53/11
    BRISTOL MYERS SQUIBB COBMY$129.7B$63.43$48.2B$7.1B38.2%2.4419.4%1.262/91/93/71/3F-Score 85/11
    BIO-TECHNE CorpTECH$11.4B$72.80$1.2B$73.4M3.8%—8.4%3.464/93/93/70/3F-Score 54/11
    REPLIGEN CORPRGEN$10.7B$167.79$738.3M$48.9M2.3%0.267.5%8.373/92/93/70/3F-Score 75/11
    IONIS PHARMACEUTICALS INCIONS$4.8B$29.06$943.7M$381.4M-78.0%3.60-40.4%3.833/91/91/70/3F-Score 43/11
    NEOGEN CORPNEOG$2.5B$11.23$870.4M$7.9M-0.4%0.76-2.5%3.823/91/92/70/3F-Score 64/11
    Pharvaris N.V.PHVS$2.4B$33.36—$206.4M-64.8%0.00——0/90/92/70/3F-Score 22/11