PRECISION BIOSCIENCES INC
DTILAbout the company
Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair.
Investment snapshot
Positive
0
BUY / PASS
Neutral / negative
2 / 14
NEUTRAL / FAIL
Median fair value
—
No comparable estimates
Models with upside
0 / 17
Positive margin of safety
Key risk
No clean pass — all 16 investors flag at least one profitability criterion
Framework analysis
| Verdict | Meaning |
|---|---|
| BUY | Positive purchase signal: the framework's buy requirements are met. |
| PASS | The company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state. |
| NEUTRAL | Neither a positive nor negative conclusion. It does not mean to hold an existing position. |
| FAIL | The company does not clear the framework's requirements. |
| Ranked | Ranked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL. |
Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.
| Metric | Graham Defensive Value | Buffett Quality Compounder | Lynch GARP | Greenblatt Magic Formula | Piotroski F-Score | Dreman Contrarian Value | Munger Quality Focus | Pabrai Dhandho Framework | Akre Three-Legged Stool | Marks Risk-Aware Value | Ackman Activist Value | Templeton Global Bargain Hunter | Sleep Scale Economies Shared | Asness Systematic Factors | Neff Low-P/E Total Return | Schloss Asset-Value Discipline | O'Shaughnessy Systematic Factor Composite |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Verdict | FAIL | FAIL | FAIL | FAIL · Rank #2915 (Top 94.1%) | FAIL | FAIL | FAIL | FAIL | FAIL | FAIL | FAIL | FAIL | FAIL | NEUTRAL | FAIL | FAIL | NEUTRAL |
| Score | |||||||||||||||||
| Analysis | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… |
| Intrinsic Value (annual) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Margin of Safety | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Financial Basis | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Annual history · FY 2025 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 · TTM ended 2026-09-30 vs 2025-09-30 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-03-12 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-03-12 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 Latest source filing: 2026-03-12 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Qualitative assessment Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-03-12 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Price history 2025-01-01–2026-11-01 · Annual history · FY 2025 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 |
Where It Passes
Where It Falls Short
- Profitability0% pass✓ 1✗ 34▾
No clean pass — all 16 investors flag at least one profitability criterion
Positive EPS (10 years)1/9 years positive✗GrahamPositive EPS every year for 10 yearsEPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthNet Income Positive (10+ years)1/9 years positive✗BuffettPositive every year for 10+ yearsROE (up to 5-year arithmetic mean)-116.1%✗Buffett> 15% arithmetic mean (app rule)Operating Margin (10-yr trend)-152.2% (latest)✓BuffettStable or rising over 10 yearsFree Cash Flow Proxy$-44.3M✗BuffettPositive and growingEarnings Variance (10-yr CoV)✗BuffettCoV < 0.3Retained Earnings Effectiveness✗Buffett$1 retained -> > $1 market value createdBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passROE-74.4%✗Lynch> 15%EBIT / Enterprise Value-26.0%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-26.0%, ROC=-12155.7%✗GreenblattBoth EY > 10% and ROC > 25%Net Income / Total Assets-29.61%✗PiotroskiROA > 0ROA Change YoY5.25% -> -29.61% (delta: -34.87%)✗PiotroskiCurrent ROA > Prior ROA(CFO / Total Assets) vs ROACFO/Assets=-42.64%, ROA=-29.61%✗PiotroskiCFO/Assets > ROAGross Margin Change YoY✗PiotroskiImproved YoYPre-Tax Income / Revenue-133.4%✗Dreman>= 8%Net Income / Shareholders' Equity-74.4%✗Dreman> 12%Margin of SafetyP/B=2.0x✗PabraiP/B < 1.5 or P/E < 15Return on Equity-120.7% (3-yr avg)✗AkreROE > 20% (3-year avg)Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePositive Net Income Frequency1/8 years positive✗MarksPositive net income in >= 7 of last 10 yearsOperating Income / Revenue-80.3%✗Ackman>= 15%Net Income / Shareholders Equity-74.4%✗Ackman>= 15%5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Operating Margin Trend-89.8% (2023) -> -152.2% (2025)✗TempletonNon-negative operating-margin trend over 3 yearsRevenue growth vs. gross and operating margin trendrevenue flat/down, operating margin -89.8% -> -152.2%✗SleepRevenue rising; gross margin flat or falling; operating margin holdingNet income / market capitalization-13.35%; #4320/6340 (top 68.1%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionGross profit / total assets✗AsnessTop 30% of eligible cross-sectionNet income / positive book equity-74.45%; #4442/5226 (top 85.0%)✗AsnessTop 30% of eligible cross-sectionNegative 5-year standard deviation of ROA-0.1846; #4152/5884 (top 70.6%)✗AsnessTop 30% of eligible cross-section3-5 Year Diluted EPS CAGR✗Neff7%-20% annualizedPositive Diluted-EPS Years1/8 years positive✗Schloss>= 70% positive over 5-10 observed years (app rule) - Valuation0% pass✓ 2✗ 26▾
No clean pass — all 13 investors flag at least one valuation criterion
Price / 3-yr avg EPS✗Graham<= 15xPrice-to-Book Ratio2.0x✗Graham<= 1.5xP/E x P/B✗Graham<= 22.5Basic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)EBIT / Enterprise Value-26.0%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-26.0%, ROC=-12155.7%✗GreenblattBoth EY > 10% and ROC > 25%Price / EPS✗Dreman< 12x✗Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)Price / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xPrice / Book Value per Share2.0x✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)Valuation ReasonablenessOE Yield=-24.3%✗MungerP/E < 25 or Owner Earnings Yield > 5%P/E or FCF YieldFCF Yield=-22.8%✗PabraiP/E < 15 or FCF Yield > 10%P/B or P/E vs. Historical AverageP/B=2.0x✓MarksP/E < 15 or P/B < 2.0Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePrice / FCF per ShareN/A (negative FCF)✗Ackman<= 25Price vs. Trailing Low191% of trailing low ($3.96)✗Templeton<= 120% of trailing low (certified split-adjusted live window)Net income / market capitalization-13.35%; #4320/6340 (top 68.1%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionPositive book equity / market capitalization+0.1793; #4296/6449 (top 66.6%)✗AsnessTop 30% of eligible cross-sectionPrice / Diluted EPS✗NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)(EPS CAGR % + Dividend Yield %) / P/E✗Neff> 0.7 (Neff's published traditional edge)Price / Tangible Book Value per Share2.00x✗SchlossP/TBV <= 1.00x (app cutoff)Book Value per Share Change+354.2%✓SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)Revenue / market capitalization+0.1560; #4015/5247 (top 76.5%)✗OshaughnessyTop 10% of eligible cross-section(Operating cash flow - capex) / market capitalization-17.94%; #3476/4519 (top 76.9%)✗OshaughnessyTop 10% of eligible cross-sectionTrailing six-month price return through the evaluation date+13.42%; #1672/6202 (top 27.0%)✗OshaughnessyTop 10% of eligible cross-section - Cash Flow0% pass✗ 12▾
All 10 investors flag DTIL's cash flow
Free Cash Flow Proxy$-44.3M✗BuffettPositive and growingFCF Positive and Growing$-51.8M✗LynchPositive and growingOperating Cash Flow$-65.8M✗PiotroskiCFO > 0(CFO / Total Assets) vs ROACFO/Assets=-42.64%, ROA=-29.61%✗PiotroskiCFO/Assets > ROAPrice / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xP/E or FCF YieldFCF Yield=-22.8%✗PabraiP/E < 15 or FCF Yield > 10%FCF Positive0/8 years FCF positive✗MarksPositive FCF in majority of recent years(OCF - CapEx) / Market Cap-28.4%✗Ackman>= 4%Price / FCF per ShareN/A (negative FCF)✗Ackman<= 25Positive Operating Cash Flow frequency0/8 years positive✗SleepPositive OCF in >= 70% of available yearsOperating Cash Flow - Capital Expenditures$-51.8M✗Neff> $0 (app proxy for a strong fundamental case)(Operating cash flow - capex) / market capitalization-17.94%; #3476/4519 (top 76.9%)✗OshaughnessyTop 10% of eligible cross-section - Growth0% pass✓ 3✗ 10▾
No clean pass — all 8 investors flag at least one growth criterion
EPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passInventory Growth vs Revenue GrowthN/A (no inventory)✓LynchInventory growth < Revenue growthEPS Growth Direction✗DremanPositive over recent yearsEPS CAGR✗Dreman> 5% annualizedPositive Net Income Frequency1/8 years positive✗MarksPositive net income in >= 7 of last 10 years3yr Median Revenue Growth41.0%✓Ackman>= 5%Positive EPS Growth Frequency2/5 years with positive EPS growth✗AckmanPositive EPS growth in >= 3 of last 5 years5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Revenue growth vs. gross and operating margin trendrevenue flat/down, operating margin -89.8% -> -152.2%✗SleepRevenue rising; gross margin flat or falling; operating margin holding5-year Revenue CAGR7.1%✓SleepCAGR > 7%3-5 Year Diluted EPS CAGR✗Neff7%-20% annualized - Verdicts0% pass✗ 15▾
Split decision: 14 FAIL · 2 NEUTRAL
Overall verdict✗GrahamFAIL (1/9)✗BuffettFAIL (1/9)✗LynchFAIL (1/7)✗GreenblattRank #2915✗PiotroskiFAIL (F-Score 2)✗DremanFAIL (2/11)✗MungerFAIL (1/4)✗PabraiFAIL (0/3)✗AkreFAIL (1/6)✗MarksFAIL (1/5)✗AckmanFAIL (3/9)✗TempletonFAIL (2/8)✗SleepFAIL (2/6)•AsnessNEUTRAL (Not ranked)✗NeffFAIL (1/6)✗SchlossFAIL (3/7)•OshaughnessyNEUTRAL (Not ranked) - Efficiency25% pass✓ 3✗ 8▾
6 of 8 flag DTIL's efficiency — Buffett, Greenblatt, Piotroski +3 more
Current Ratio10.47✓Graham>= 2.0ROIC (3-5 yr avg)-1075.9%✗Buffett> 10%ROIC - WACC-1085.9%✗BuffettPositive (WACC = 10%)EBIT / (NWC + Net Fixed Assets)-12155.7%✗Greenblatt> 25%Current Ratio Change YoY6.34 -> 13.32✓PiotroskiIncreased YoYRevenue / Total Assets Change YoY0.50x -> 0.22x✗PiotroskiImproved YoYCurrent Assets / Current Liabilities10.47✓Dreman> 1.5Return on Invested Capital-38.5%✗Munger> 15%ROIC (high and growing)FY2023: ROIC=-83.7%; FY2024: ROIC=-26.3%; FY2025: ROIC=-35.9%✗AkreLatest 3 consecutive FYs: ROIC > 15% in eachReinvestment Rate x ROICN/A (non-positive net income)✗AkreReinvestment Rate * ROIC > 10%ROIC (5-year)0/5 years above 12% (latest -35.9%)✗SleepROIC > 12% in a majority of years - Debt & Leverage50% pass✓ 8✗ 7▾
6 of 12 pass — Graham, Buffett, Lynch +3 more object
Debt Levels0.43✓MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3LT Debt vs Net Current Assets✗GrahamLT Debt <= Net Current AssetsDebt/Equity & Interest CoverageD/E: 0.43, IC: -28.6x✗BuffettD/E < 0.5 AND Interest Coverage > 5xTotal Debt / Equity0.43✗Lynch< 0.33Cash - Long-term Debt✗LynchPositive preferredLT Debt / Total Assets Change0.00% -> 0.00%✓PiotroskiDecreased YoYCurrent Assets / Current Liabilities10.47✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)Total Debt / Shareholders' Equity0.43✓Dreman< 0.8✓Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✓SchlossD/E < 1.00xInterest Coverage & Debt/EBITDAIC=-28.6x, D/EBITDA=N/A✗MarksInterest Coverage > 3x; Debt/EBITDA < 4xTotal Debt / Shareholders Equity0.43✓Ackman<= 1.0Negative debt-to-equity (higher means less debt)-0.4331; #2322/4210 (top 55.2%)✗AsnessTop 30% of eligible cross-section
Business & financials
Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.
Company Profile
Financial Snapshot
Shareholder Return
Fiscal 2025
Issued 193.7% of shares last year.
- Buybacks
- —
- Dividends
- —
Company Financials
Latest TTM and quarters alongside annual years
TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.
The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.
| Metric | TTM · 2026-09-30 2025-10-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: revenue, net income, operating income, ebit, interest expense, operating cash flow, depreciation amortization, capex. | Q3 FY 2026 2026-07-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, depreciation amortization, capex. | Q2 FY 2026 2026-04-01 – 2026-06-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, depreciation amortization, capex. | Q1 FY 2026 2026-01-01 – 2026-03-31 Sources | FY 2025Sources
| FY 2024Sources
| FY 2023Sources
| FY 2022Sources
| FY 2021Sources
|
|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $288.8Mcurrent | -- | -- | -- | $95.4Mest. | $41.1Mest. | $47.1Mest. | $3.9Best. | $8.7Best. |
| Revenue | $45.0M↑6353% | $0↓100% | $0↓100% | $10.8M↑37272% | $34.3M↓50% | $68.7M↑41% | $48.7M↑94% | $25.1M↓78% | $115.5M |
| Operating Income | -$36.2M↑60% | -$20.4M↑1% | -$19.2M↑12% | -$9.1M↑59% | -$52.1M↓99% | -$26.2M↑40% | -$43.7M↑30% | -$62.3M↓58% | -$39.4M |
| Net Income | -$38.5M↑54% | -$7.6M↑65% | -$32.7M↓39% | -$18.4M↑10% | -$45.7M↓738% | $7.2M↑112% | -$61.3M↑45% | -$111.6M↓265% | -$30.6M |
| EPS (Diluted) | -- | $-0.28↑85% | $-1.26↑41% | $-0.75↑66% | $-3.56↓442% | $1.04↑107% | $-15.96↓1157% | $-1.27↓144% | $-0.52 |
| Gross Margin | — | — | — | — | — | — | — | — | — |
| Operating Margin | -80.3%↑99% | — | — | -83.7%↑100% | -152.2%↓300% | -38.1%↑58% | -89.8%↑64% | -248.3%↓628% | -34.1% |
| ROE | -74.4%↑85% | — | — | — | -49.6%↓490% | 12.7%↑104% | -325.1%↓76% | -184.7%↓450% | -33.6% |
| Total Debt | $22.4M | $22.4M | $22.4M | $22.4M | $22.4M | $22.3M | $22.4M↑1% | $22.2M↑797% | $2.5M |
| Shareholders' Equity | $51.8M↑211% | $51.8M↑211% | $45.3M↑33% | $76.1M↑54% | $92.2M↑64% | $56.4M↑199% | $18.9M↓69% | $60.4M↓34% | $91.2M |
| Current Ratio | 10.47↑204% | 10.47↑204% | 12.82↑148% | 14.02↑112% | 13.32↑110% | 6.34↑132% | 2.73↓18% | 3.34↓26% | 4.50 |
| Debt / Equity | 0.43↓68% | 0.43↓68% | 0.50↓25% | 0.29↓35% | 0.24↓39% | 0.40↓67% | 1.19↑223% | 0.37↑1253% | 0.03 |
| Operating Cash Flow | -$51.8M↑29% | -$15.1M↑1% | -$13.4M↑34% | -$11.9M↑37% | -$65.8M↓13% | -$58.4M↑31% | -$84.1M↓84% | -$45.8M↓322% | -$10.9M |
| Free Cash Flow | -$51.8M↑29% | -$15.1M↑1% | -$13.4M↑34% | -$12.0M↑37% | -$65.9M↓12% | -$58.7M↑32% | -$86.1M↓75% | -$49.1M↓209% | -$15.9M |
Score history
Historical Score Timeline
Industry peers
Industry Peers
Similar companies in Pharmaceutical Products
DTIL vs Peers — Financial Grading
| Company | Market Cap | Price | Revenue | Net Income | ROE | D/E | Op. Margin | Curr. Ratio | Graham | Buffett | Lynch | Greenblatt | Piotroski | Dreman |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck & Co., Inc.MRK | $364.3B | $147.76 | $65.0B | $18.3B | 34.7% | 0.94 | — | 1.54 | 2/9 | 5/9 | 4/7 | 0/3 | F-Score 4 | 1/11 |
| ABBOTT LABORATORIESABT | $188.0B | $108.52 | $44.3B | $6.5B | 12.5% | 0.25 | 18.2% | 1.58 | 3/9 | 4/9 | 2/7 | 1/3 | F-Score 5 | 3/11 |
| BRISTOL MYERS SQUIBB COBMY | $129.7B | $63.43 | $48.2B | $7.1B | 38.2% | 2.44 | 19.4% | 1.26 | 2/9 | 1/9 | 3/7 | 1/3 | F-Score 8 | 5/11 |
| BIO-TECHNE CorpTECH | $11.4B | $72.80 | $1.2B | $73.4M | 3.8% | — | 8.4% | 3.46 | 4/9 | 3/9 | 3/7 | 0/3 | F-Score 5 | 4/11 |
| REPLIGEN CORPRGEN | $10.7B | $167.79 | $738.3M | $48.9M | 2.3% | 0.26 | 7.5% | 8.37 | 3/9 | 2/9 | 3/7 | 0/3 | F-Score 7 | 5/11 |
| IONIS PHARMACEUTICALS INCIONS | $4.8B | $29.06 | $943.7M | $381.4M | -78.0% | 3.60 | -40.4% | 3.83 | 3/9 | 1/9 | 1/7 | 0/3 | F-Score 4 | 3/11 |
| NEOGEN CORPNEOG | $2.5B | $11.23 | $870.4M | $7.9M | -0.4% | 0.76 | -2.5% | 3.82 | 3/9 | 1/9 | 2/7 | 0/3 | F-Score 6 | 4/11 |
| Pharvaris N.V.PHVS | $2.4B | $33.36 | — | $206.4M | -64.8% | 0.00 | — | — | 0/9 | 0/9 | 2/7 | 0/3 | F-Score 2 | 2/11 |