KYNTRA BIO, INC.

KYNB
About the company

Kyntra Bio, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapeutics to treat serious unmet medical needs. The company is developing FG-3246, a potential antibody-drug conjugate targeting CD46, for the treatment of metastatic castration-resistant prostate cancer and other cancers.

Country: United StatesPrice: $3.44Market Cap: $13.9M

Investment snapshot

12%positive consensus
Scored 1d ago

Positive

2

BUY / PASS

Neutral / negative

3 / 11

NEUTRAL / FAIL

Median fair value

—

No comparable estimates

Models with upside

0 / 17

Positive margin of safety

Key risk

No clean pass — all 12 investors flag at least one debt & leverage criterion

Framework analysis

VerdictMeaning
BUYPositive purchase signal: the framework's buy requirements are met.
PASSThe company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state.
NEUTRALNeither a positive nor negative conclusion. It does not mean to hold an existing position.
FAILThe company does not clear the framework's requirements.
RankedRanked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL.

Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.

MetricGraham

Defensive Value

Buffett

Quality Compounder

Lynch

GARP

Greenblatt

Magic Formula

Piotroski

F-Score

Dreman

Contrarian Value

Munger

Quality Focus

Pabrai

Dhandho Framework

Akre

Three-Legged Stool

Marks

Risk-Aware Value

Ackman

Activist Value

Templeton

Global Bargain Hunter

Sleep

Scale Economies Shared

Asness

Systematic Factors

Neff

Low-P/E Total Return

Schloss

Asset-Value Discipline

O'Shaughnessy

Systematic Factor Composite

VerdictFAILFAILFAILNot rankedPASSFAILPASSNEUTRALFAILFAILFAILFAILFAILNEUTRALFAILFAILNEUTRAL
Score
AnalysisChecking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…Checking access…
Intrinsic Value (annual)N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Margin of SafetyN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Financial Basis

TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Annual history · FY 2025

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30 vs 2025-06-30 · TTM ended 2026-06-30

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Market data at 2026-11-01

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment · TTM ended 2026-06-30

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30 · Market data at 2026-11-01

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025 · Price history 2025-01-01–2026-11-01

Latest source filing: 2026-03-16

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-16

Score computed: 2026-11-14

TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Price history 2025-01-01–2026-11-01 · Annual history · FY 2025

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Annual history · FY 2025 · Balance sheet at 2026-06-30

Latest source filing: 2026-08-13

Score computed: 2026-11-14

TTM ended 2026-06-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-11-01

Latest source filing: 2026-08-13

Score computed: 2026-11-14

Where It Passes

    Where It Falls Short

    • Debt & Leverage0% pass✓ 2✗ 13▾

      No clean pass — all 12 investors flag at least one debt & leverage criterion

      LT Debt vs Net Current AssetsLT Debt $75.0M vs NCA $69.8M
      ✗GrahamLT Debt <= Net Current Assets
      Debt/Equity & Interest CoverageD/E: N/A (negative equity), IC: -5.2x
      ✗BuffettD/E < 0.5 AND Interest Coverage > 5x
      Total Debt / EquityN/A (negative equity)
      ✗Lynch< 0.33
      Cash - Long-term Debt$-27.1M
      ✗LynchPositive preferred
      LT Debt / Total Assets Change0.00% -> 62.71%
      ✗PiotroskiDecreased YoY
      Current Assets / Current Liabilities2.69
      ✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)
      Total Debt / Shareholders' Equity
      ✗Dreman< 0.8✗Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✗SchlossD/E < 1.00x
      Debt LevelsN/A (non-positive equity)
      ✗MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3
      Interest Coverage & Debt/EBITDAIC=-5.2x, D/EBITDA=N/A (D&A unavailable)
      ✗MarksInterest Coverage > 3x; Debt/EBITDA < 4x
      Total Debt / Shareholders Equity
      ✗Ackman<= 1.0
      Negative debt-to-equity (higher means less debt)
      ✗AsnessTop 30% of eligible cross-section
    • Growth0% pass✓ 1✗ 12▾

      No clean pass — all 8 investors flag at least one growth criterion

      EPS Growth (3-yr avg, 10-yr window)
      ✗Graham>= 33% growth
      Basic earnings-growth PEG (dividends excluded)P/E 0.1x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      3-5 Year EPS CAGR
      ✗Lynch15-30% (Fast Grower); > 0% to pass
      Inventory Growth vs Revenue GrowthInv: -12.4% vs Rev: 106.3%
      ✓LynchInventory growth < Revenue growth
      EPS Growth Direction
      ✗DremanPositive over recent years
      EPS CAGR
      ✗Dreman> 5% annualized
      Positive Net Income Frequency1/13 years positive
      ✗MarksPositive net income in >= 7 of last 10 years
      3yr Median Revenue Growth-66.7%
      ✗Ackman>= 5%
      Positive EPS Growth Frequency
      ✗AckmanPositive EPS growth in >= 3 of last 5 years
      5-Year EPS CAGR
      ✗Templeton> 0% (5-year EPS CAGR)
      Revenue growth vs. gross and operating margin trendgross margin 91.5% -> 91.4%, operating margin -689.5% -> -712.7%
      ✗SleepRevenue rising; gross margin flat or falling; operating margin holding
      5-year Revenue CAGR-48.4%
      ✗SleepCAGR > 7%
      3-5 Year Diluted EPS CAGR
      ✗Neff7%-20% annualized
    • Cash Flow10% pass✓ 1✗ 11▾

      9 of 10 flag KYNB's cash flow — Buffett, Lynch, Piotroski +6 more

      Free Cash Flow Proxy
      ✗BuffettPositive and growing
      FCF Positive and Growing$-38.1M
      ✗LynchPositive and growing
      Operating Cash Flow$-4.8M
      ✗PiotroskiCFO > 0
      (CFO / Total Assets) vs ROACFO/Assets=-3.99%, ROA=153.40%
      ✗PiotroskiCFO/Assets > ROA
      Price / (CFO / Shares)N/A (negative CFPS)
      ✗Dreman< 8x
      P/E or FCF YieldP/E=0.1x, FCF Yield=-34.5%
      ✓PabraiP/E < 15 or FCF Yield > 10%
      FCF Positive4/13 years FCF positive
      ✗MarksPositive FCF in majority of recent years
      (OCF - CapEx) / Market Cap-273.4%
      ✗Ackman>= 4%
      Price / FCF per ShareN/A (negative FCF)
      ✗Ackman<= 25
      Positive Operating Cash Flow frequency4/13 years positive
      ✗SleepPositive OCF in >= 70% of available years
      Operating Cash Flow - Capital Expenditures$-38.1M
      ✗Neff> $0 (app proxy for a strong fundamental case)
      (Operating cash flow - capex) / market capitalization-273.26%; #4262/4519 (top 94.3%)
      ✗OshaughnessyTop 10% of eligible cross-section
    • Profitability13% pass✓ 6✗ 29▾

      14 of 16 flag KYNB's profitability — Graham, Buffett, Lynch +11 more

      Positive EPS (10 years)1/14 years positive
      ✗GrahamPositive EPS every year for 10 years
      EPS Growth (3-yr avg, 10-yr window)
      ✗Graham>= 33% growth
      Net Income Positive (10+ years)1/14 years positive
      ✗BuffettPositive every year for 10+ years
      ROE (up to 5-year arithmetic mean)-47.7%
      ✗Buffett> 15% arithmetic mean (app rule)
      Operating Margin (10-yr trend)-712.7% (latest)
      ✗BuffettStable or rising over 10 years
      Free Cash Flow Proxy
      ✗BuffettPositive and growing
      Earnings Variance (10-yr CoV)
      ✗BuffettCoV < 0.3
      Retained Earnings Effectiveness
      ✗Buffett$1 retained -> > $1 market value created
      Basic earnings-growth PEG (dividends excluded)P/E 0.1x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      3-5 Year EPS CAGR
      ✗Lynch15-30% (Fast Grower); > 0% to pass
      ROEN/A (negative equity)
      ✗Lynch> 15%
      EBIT / Enterprise Value-111.8%
      ✗Greenblatt> 10%
      Earnings Yield + ROC AssessmentEY=-111.8%, ROC=None
      ✗GreenblattBoth EY > 10% and ROC > 25%
      Net Income / Total Assets153.40%
      ✓PiotroskiROA > 0
      ROA Change YoY-22.18% -> 153.40% (delta: +175.57%)
      ✓PiotroskiCurrent ROA > Prior ROA
      (CFO / Total Assets) vs ROACFO/Assets=-3.99%, ROA=153.40%
      ✗PiotroskiCFO/Assets > ROA
      Gross Margin Change YoY47.5% -> 91.4%
      ✓PiotroskiImproved YoY
      Pre-Tax Income / Revenue-669.6%
      ✗Dreman>= 8%
      Net Income / Shareholders' Equity
      ✗Dreman> 12%
      Margin of SafetyP/E=0.1x
      ✓PabraiP/B < 1.5 or P/E < 15
      Return on Equity-66.1% (3-yr avg)
      ✗AkreROE > 20% (3-year avg)
      Discount to Intrinsic Value
      ✗Marks>= 20% below intrinsic value
      Positive Net Income Frequency1/13 years positive
      ✗MarksPositive net income in >= 7 of last 10 years
      Operating Income / Revenue-1089.8%
      ✗Ackman>= 15%
      Net Income / Shareholders Equity
      ✗Ackman>= 15%
      5-Year EPS CAGR
      ✗Templeton> 0% (5-year EPS CAGR)
      Operating Margin Trend-689.5% (2023) -> -712.7% (2025)
      ✗TempletonNon-negative operating-margin trend over 3 years
      Revenue growth vs. gross and operating margin trendgross margin 91.5% -> 91.4%, operating margin -689.5% -> -712.7%
      ✗SleepRevenue rising; gross margin flat or falling; operating margin holding
      Net income / market capitalization+1315.19%; #20/6340 (top 0.3%)
      ✓AsnessTop 30% of eligible cross-section✓OshaughnessyTop 10% of eligible cross-section
      Gross profit / total assets+4.92%; #3101/3702 (top 83.8%)
      ✗AsnessTop 30% of eligible cross-section
      Net income / positive book equity
      ✗AsnessTop 30% of eligible cross-section
      Negative 5-year standard deviation of ROA-0.8019; #5180/5884 (top 88.0%)
      ✗AsnessTop 30% of eligible cross-section
      3-5 Year Diluted EPS CAGR
      ✗Neff7%-20% annualized
      Positive Diluted-EPS Years1/10 years positive
      ✗Schloss>= 70% positive over 5-10 observed years (app rule)
    • Valuation15% pass✓ 9✗ 19▾

      11 of 13 flag KYNB's valuation — Graham, Lynch, Greenblatt +8 more

      Price / 3-yr avg EPS
      ✗Graham<= 15x
      Price-to-Book Ratio
      ✗Graham<= 1.5x
      P/E x P/B
      ✗Graham<= 22.5
      Basic earnings-growth PEG (dividends excluded)P/E 0.1x (growth N/A)
      ✗Lynch< 1.0 (ideally < 0.5)
      EBIT / Enterprise Value-111.8%
      ✗Greenblatt> 10%
      Earnings Yield + ROC AssessmentEY=-111.8%, ROC=None
      ✗GreenblattBoth EY > 10% and ROC > 25%
      Price / EPS0.1x
      ✓Dreman< 12x✓Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)
      Price / (CFO / Shares)N/A (negative CFPS)
      ✗Dreman< 8x
      Price / Book Value per ShareN/A (negative BVPS)
      ✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)
      Valuation ReasonablenessP/E=0.1x
      ✓MungerP/E < 25 or Owner Earnings Yield > 5%
      P/E or FCF YieldP/E=0.1x, FCF Yield=-34.5%
      ✓PabraiP/E < 15 or FCF Yield > 10%
      P/B or P/E vs. Historical AverageP/E=0.1x
      ✓MarksP/E < 15 or P/B < 2.0
      Discount to Intrinsic Value
      ✗Marks>= 20% below intrinsic value
      Price / FCF per ShareN/A (negative FCF)
      ✗Ackman<= 25
      Price vs. Trailing Low100% of trailing low ($3.44)
      ✓Templeton<= 120% of trailing low (certified split-adjusted live window)
      Net income / market capitalization+1315.19%; #20/6340 (top 0.3%)
      ✓AsnessTop 30% of eligible cross-section✓OshaughnessyTop 10% of eligible cross-section
      Positive book equity / market capitalization-2.1641; #6133/6449 (top 95.1%)
      ✗AsnessTop 30% of eligible cross-section
      Price / Diluted EPS0.1x
      ✓NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)
      (EPS CAGR % + Dividend Yield %) / P/E
      ✗Neff> 0.7 (Neff's published traditional edge)
      Price / Tangible Book Value per ShareN/A (non-positive TBVPS)
      ✗SchlossP/TBV <= 1.00x (app cutoff)
      Book Value per Share Change
      ✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)
      Revenue / market capitalization+0.3315; #3174/5247 (top 60.5%)
      ✗OshaughnessyTop 10% of eligible cross-section
      (Operating cash flow - capex) / market capitalization-273.26%; #4262/4519 (top 94.3%)
      ✗OshaughnessyTop 10% of eligible cross-section
      Trailing six-month price return through the evaluation date-52.02%; #5206/6202 (top 83.9%)
      ✗OshaughnessyTop 10% of eligible cross-section
    • Verdicts15% pass✓ 2✗ 11▾

      Split decision: 11 FAIL · 3 NEUTRAL · 2 PASS

      Overall verdict
      ✗GrahamFAIL (1/9)✗BuffettFAIL (0/9)✗LynchFAIL (1/7)•GreenblattNot ranked✓PiotroskiPASS (F-Score 4)✗DremanFAIL (2/11)✓MungerPASS (2/4)•PabraiNEUTRAL (2/3)✗AkreFAIL (1/6)✗MarksFAIL (1/5)✗AckmanFAIL (1/9)✗TempletonFAIL (3/8)✗SleepFAIL (1/6)•AsnessNEUTRAL (Not ranked)✗NeffFAIL (1/6)✗SchlossFAIL (1/7)•OshaughnessyNEUTRAL (Not ranked)
    • Efficiency25% pass✓ 3✗ 8▾

      6 of 8 flag KYNB's efficiency — Buffett, Greenblatt, Piotroski +3 more

      Current Ratio2.69
      ✓Graham>= 2.0
      ROIC (3-5 yr avg)-170.7%
      ✗Buffett> 10%
      ROIC - WACC-180.7%
      ✗BuffettPositive (WACC = 10%)
      EBIT / (NWC + Net Fixed Assets)
      ✗Greenblatt> 25%
      Current Ratio Change YoY1.47 -> 3.39
      ✓PiotroskiIncreased YoY
      Revenue / Total Assets Change YoY0.14x -> 0.05x
      ✗PiotroskiImproved YoY
      Current Assets / Current Liabilities2.69
      ✓Dreman> 1.5
      Return on Invested Capital-80.6%
      ✗Munger> 15%
      ROIC (high and growing)FY2023: ROIC=unavailable; FY2024: ROIC=unavailable; FY2025: ROIC=-80.6%
      ✗AkreLatest 3 consecutive FYs: ROIC > 15% in each
      Reinvestment Rate x ROIC-80.6% (RR=100% x ROIC=-80.6%)
      ✗AkreReinvestment Rate * ROIC > 10%
      ROIC (5-year)0/2 years above 12% (latest -80.6%)
      ✗SleepROIC > 12% in a majority of years

    Business & financials

    Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.

    Company Profile

    Industry: Pharmaceutical Products
    SIC Sector: Chemicals & Pharmaceuticals
    Size: Micro Cap($13.9M)
    Revenue: $6.4M-78.3% YoY
    Net Income: $183.5M+485.6% YoY

    Financial Snapshot

    Operating Margin-712.7%
    Return on Equity-610.7%
    Debt / Equity-2.50
    Current Ratio3.39
    EPS (Diluted)$45.37

    Company Financials

    Latest TTM and quarters alongside annual years

    TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.

    The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.

    MetricTTM · 2026-06-30

    2025-07-01 – 2026-06-30

    Sources · derived quarter values

    Derived from cumulative filings: operating cash flow, capex, revenue, net income, operating income, ebit, pre tax income, interest expense.

    Q2 FY 2026

    2026-04-01 – 2026-06-30

    Sources · derived quarter values

    Derived from cumulative filings: operating cash flow, capex.

    Q1 FY 2026

    2026-01-01 – 2026-03-31

    Sources
    FY 2025
    Sources
    • 10-K · 2026-03-16
    FY 2024
    Sources
    • 10-K · 2025-03-17
    FY 2023
    Sources
    • 10-K · 2024-02-26
    FY 2022
    Sources
    • 10-K · 2023-02-27
    FY 2021
    Sources
    • 10-K · 2022-02-28
    Market Cap$13.9Mcurrent----$31.9Mest.$1.2Best.$4.7Best.$55.6Best.$35.1Best.
    Revenue$4.6M↑106%-$1.5M↓209%$3.7M↑36%$6.4M↓78%$29.6M↓37%$46.8M↓67%$140.7M↓40%$235.3M
    Operating Income-$50.3M↑63%-$17.6M↓46%-$13.8M↑7%-$45.9M↑69%-$150.4M↑53%-$322.7M↓7%-$301.0M↓4%-$288.5M
    Net Income$183.2M↑8967%$12.0M↑257%-$15.2M↓428%$183.5M↑486%-$47.6M↑83%-$284.2M↑3%-$293.7M↓1%-$290.0M
    EPS (Diluted)--$2.96↑257%$-3.76↓7620%$45.37↑9552%$-0.48↑84%$-2.92↑7%$-3.14$-3.14
    Gross Margin———91.4%↑92%47.5%↓48%91.5%↑7%85.6%↓9%94.5%
    Operating Margin-1089.8%↓686%1192.3%↑233%-369.7%↑32%-712.7%↓40%-507.8%↑26%-689.5%↓222%-213.9%↓74%-122.6%
    ROE-607.7%↓65696%——-610.7%↓2996%21.1%↓85%139.2%↓90%1369.2%↑1087%-138.7%
    Total Debt------$75.0M↑72015%$104.0K↓23%$135.0K↓22%$173.0K↑1136%$14.0K
    Shareholders' Equity-$30.1M↑86%-$30.1M↑86%-$43.8M↑80%-$30.0M↑87%-$225.6M↓10%-$204.2M↓852%-$21.4M↓110%$209.1M
    Current Ratio2.69↑158%2.69↑158%3.61↑78%3.39↑130%1.47↓3%1.52↓15%1.80↓14%2.10
    Debt / Equity———-2.50↓541526%-0.00↑30%-0.00↑92%-0.01↓12150%0.00
    Operating Cash Flow-$38.1M↓62%-$4.0M↓131%-$13.9M↓611%-$4.8M↑97%-$138.0M↑56%-$315.0M↓116%-$145.9M↓77%-$82.2M
    Free Cash Flow-$38.1M↓61%-$4.0M↓132%-$13.9M↓614%-$4.8M↑97%-$138.3M↑56%-$317.5M↓112%-$149.7M↓71%-$87.4M

    Score history

    Historical Score Timeline

    Industry peers

    Industry Peers

    Similar companies in Pharmaceutical Products

    KYNB vs Peers — Financial Grading

    Revenue$6.4MBottom 25%
    Net Income$183.5MMedian
    ROE-610.7%Bottom 25%
    D/E-2.50Top 25%
    Op. Margin-712.7%Bottom 25%
    Curr. Ratio3.39Median
    CompanyMarket CapPriceRevenueNet IncomeROED/EOp. MarginCurr. RatioGrahamBuffettLynchGreenblattPiotroskiDreman
    Merck & Co., Inc.MRK$364.3B$147.76$65.0B$18.3B34.7%0.94—1.542/95/94/70/3F-Score 41/11
    ABBOTT LABORATORIESABT$188.0B$108.52$44.3B$6.5B12.5%0.2518.2%1.583/94/92/71/3F-Score 53/11
    BRISTOL MYERS SQUIBB COBMY$129.7B$63.43$48.2B$7.1B38.2%2.4419.4%1.262/91/93/71/3F-Score 85/11
    BIO-TECHNE CorpTECH$11.4B$72.80$1.2B$73.4M3.8%—8.4%3.464/93/93/70/3F-Score 54/11
    REPLIGEN CORPRGEN$10.7B$167.79$738.3M$48.9M2.3%0.267.5%8.373/92/93/70/3F-Score 75/11
    IONIS PHARMACEUTICALS INCIONS$4.8B$29.06$943.7M$381.4M-78.0%3.60-40.4%3.833/91/91/70/3F-Score 43/11
    NEOGEN CORPNEOG$2.5B$11.23$870.4M$7.9M-0.4%0.76-2.5%3.823/91/92/70/3F-Score 64/11
    Pharvaris N.V.PHVS$2.4B$33.36—$206.4M-64.8%0.00——0/90/92/70/3F-Score 22/11