Tarsus Pharmaceuticals, Inc.
TARSAbout the company
Tarsus Pharmaceuticals, Inc., a commercial stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for eye care in the United States. The company offers XDEMVY, a lotilaner ophthalmic solution for the treatment of demodex blepharitis caused by the infestation of Demodex mites.
Investment snapshot
Positive
2
BUY / PASS
Neutral / negative
2 / 12
NEUTRAL / FAIL
Median fair value
—
No comparable estimates
Models with upside
0 / 17
Positive margin of safety
Key risk
All 13 investors flag TARS's valuation
Framework analysis
| Verdict | Meaning |
|---|---|
| BUY | Positive purchase signal: the framework's buy requirements are met. |
| PASS | The company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state. |
| NEUTRAL | Neither a positive nor negative conclusion. It does not mean to hold an existing position. |
| FAIL | The company does not clear the framework's requirements. |
| Ranked | Ranked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL. |
Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.
| Metric | Graham Defensive Value | Buffett Quality Compounder | Lynch GARP | Greenblatt Magic Formula | Piotroski F-Score | Dreman Contrarian Value | Munger Quality Focus | Pabrai Dhandho Framework | Akre Three-Legged Stool | Marks Risk-Aware Value | Ackman Activist Value | Templeton Global Bargain Hunter | Sleep Scale Economies Shared | Asness Systematic Factors | Neff Low-P/E Total Return | Schloss Asset-Value Discipline | O'Shaughnessy Systematic Factor Composite |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Verdict | FAIL | FAIL | FAIL | FAIL · Rank #2795 (Top 90.2%) | PASS | FAIL | FAIL | FAIL | FAIL | FAIL | PASS | FAIL | FAIL | NEUTRAL | FAIL | FAIL | NEUTRAL |
| Score | |||||||||||||||||
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| Intrinsic Value (annual) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Margin of Safety | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Financial Basis | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Annual history · FY 2025 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 · TTM ended 2026-09-30 vs 2025-09-30 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-02-23 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 Latest source filing: 2026-02-23 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-02-23 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-02-23 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Price history 2025-01-01–2026-11-01 · Annual history · FY 2025 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-03 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 Latest source filing: 2026-11-03 Score computed: 2026-11-14 |
Where It Passes
Where It Falls Short
- Valuation0% pass✗ 28▾
All 13 investors flag TARS's valuation
Price / 3-yr avg EPS✗Graham<= 15xPrice-to-Book Ratio9.9x✗Graham<= 1.5xP/E x P/B✗Graham<= 22.5Basic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)EBIT / Enterprise Value-17.9%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-17.9%, ROC=-679.2%✗GreenblattBoth EY > 10% and ROC > 25%Price / EPS✗Dreman< 12x✗Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)Price / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xPrice / Book Value per Share9.9x✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)Valuation Reasonableness✗MungerP/E < 25 or Owner Earnings Yield > 5%P/E or FCF YieldFCF Yield=-0.6%✗PabraiP/E < 15 or FCF Yield > 10%P/B or P/E vs. Historical AverageP/B=9.9x✗MarksP/E < 15 or P/B < 2.0Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePrice / FCF per ShareN/A (negative FCF)✗Ackman<= 25Price vs. Trailing Low207% of trailing low ($38.82)✗Templeton<= 120% of trailing low (certified split-adjusted live window)Net income / market capitalization-17.74%; #4491/6340 (top 70.8%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionPositive book equity / market capitalization+0.0263; #5104/6449 (top 79.1%)✗AsnessTop 30% of eligible cross-sectionPrice / Diluted EPS✗NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)(EPS CAGR % + Dividend Yield %) / P/E✗Neff> 0.7 (Neff's published traditional edge)Price / Tangible Book Value per Share10.17x✗SchlossP/TBV <= 1.00x (app cutoff)Book Value per Share Change-69.8%✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)Revenue / market capitalization+0.1723; #3917/5247 (top 74.7%)✗OshaughnessyTop 10% of eligible cross-section(Operating cash flow - capex) / market capitalization+0.82%; #2426/4519 (top 53.7%)✗OshaughnessyTop 10% of eligible cross-sectionTrailing six-month price return through the evaluation date+10.64%; #1829/6202 (top 29.5%)✗OshaughnessyTop 10% of eligible cross-section - Profitability6% pass✓ 4✗ 31▾
15 of 16 flag TARS's profitability — Graham, Buffett, Lynch +12 more
Positive EPS (10 years)0/9 years positive✗GrahamPositive EPS every year for 10 yearsEPS Growth (3-yr avg, 10-yr window)N/A (negative base EPS)✗Graham>= 33% growthNet Income Positive (10+ years)0/9 years positive✗BuffettPositive every year for 10+ yearsROE (up to 5-year arithmetic mean)-36.1%✗Buffett> 15% arithmetic mean (app rule)Operating Margin (10-yr trend)-15.7% (latest)✗BuffettStable or rising over 10 yearsFree Cash Flow Proxy$-13.8M✗BuffettPositive and growingEarnings Variance (10-yr CoV)N/A (negative mean EPS)✗BuffettCoV < 0.3Retained Earnings Effectiveness✗Buffett$1 retained -> > $1 market value createdBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passROE-675.0%✗Lynch> 15%EBIT / Enterprise Value-17.9%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-17.9%, ROC=-679.2%✗GreenblattBoth EY > 10% and ROC > 25%Net Income / Total Assets-11.81%✗PiotroskiROA > 0ROA Change YoY-30.65% -> -11.81% (delta: +18.84%)✓PiotroskiCurrent ROA > Prior ROA(CFO / Total Assets) vs ROACFO/Assets=-2.21%, ROA=-11.81%✓PiotroskiCFO/Assets > ROAGross Margin Change YoY✗PiotroskiImproved YoYPre-Tax Income / Revenue-14.3%✗Dreman>= 8%Net Income / Shareholders' Equity-675.0%✗Dreman> 12%Margin of SafetyP/B=9.9x✗PabraiP/B < 1.5 or P/E < 15Return on Equity-46.6% (3-yr avg)✗AkreROE > 20% (3-year avg)Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePositive Net Income Frequency0/8 years positive✗MarksPositive net income in >= 7 of last 10 yearsOperating Income / Revenue-102.0%✗Ackman>= 15%Net Income / Shareholders Equity-675.0%✗Ackman>= 15%5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Operating Margin Trend-820.5% (2023) -> -15.7% (2025)✓TempletonNon-negative operating-margin trend over 3 yearsRevenue growth vs. gross and operating margin trendrevenue up, operating margin -820.5% -> -15.7%✓SleepRevenue rising; gross margin flat or falling; operating margin holdingNet income / market capitalization-17.74%; #4491/6340 (top 70.8%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionGross profit / total assets✗AsnessTop 30% of eligible cross-sectionNet income / positive book equity-675.03%; #5118/5226 (top 97.9%)✗AsnessTop 30% of eligible cross-sectionNegative 5-year standard deviation of ROA-0.1544; #3964/5884 (top 67.4%)✗AsnessTop 30% of eligible cross-section3-5 Year Diluted EPS CAGR✗Neff7%-20% annualizedPositive Diluted-EPS Years0/7 years positive✗Schloss>= 70% positive over 5-10 observed years (app rule) - Growth13% pass✓ 4✗ 9▾
7 of 8 flag TARS's growth — Graham, Lynch, Dreman +4 more
EPS Growth (3-yr avg, 10-yr window)N/A (negative base EPS)✗Graham>= 33% growthBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passInventory Growth vs Revenue GrowthInv: 34.5% vs Rev: 86.3%✓LynchInventory growth < Revenue growthEPS Growth Direction$-1.98 (2019) -> $-1.59 (2025)✗DremanPositive over recent yearsEPS CAGR✗Dreman> 5% annualizedPositive Net Income Frequency0/8 years positive✗MarksPositive net income in >= 7 of last 10 years3yr Median Revenue Growth146.7%✓Ackman>= 5%Positive EPS Growth Frequency3/5 years with positive EPS growth✓AckmanPositive EPS growth in >= 3 of last 5 years5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Revenue growth vs. gross and operating margin trendrevenue up, operating margin -820.5% -> -15.7%✓SleepRevenue rising; gross margin flat or falling; operating margin holding5-year Revenue CAGR✗SleepCAGR > 7%3-5 Year Diluted EPS CAGR✗Neff7%-20% annualized - Efficiency13% pass✓ 2✗ 9▾
7 of 8 flag TARS's efficiency — Graham, Buffett, Greenblatt +4 more
Current Ratio1.96✗Graham>= 2.0ROIC (3-5 yr avg)-1546.7%✗Buffett> 10%ROIC - WACC-1556.7%✗BuffettPositive (WACC = 10%)EBIT / (NWC + Net Fixed Assets)-679.2%✗Greenblatt> 25%Current Ratio Change YoY4.42 -> 3.85✗PiotroskiIncreased YoYRevenue / Total Assets Change YoY0.49x -> 0.80x✓PiotroskiImproved YoYCurrent Assets / Current Liabilities1.96✓Dreman> 1.5Return on Invested Capital-310.8%✗Munger> 15%ROIC (high and growing)FY2023: ROIC=-49.9%; FY2024: ROIC=-32.1%; FY2025: ROIC=-13.5%✗AkreLatest 3 consecutive FYs: ROIC > 15% in eachReinvestment Rate x ROICN/A (non-positive net income)✗AkreReinvestment Rate * ROIC > 10%ROIC (5-year)0/5 years above 12% (latest -13.5%)✗SleepROIC > 12% in a majority of years - Verdicts13% pass✓ 2✗ 13▾
Split decision: 12 FAIL · 2 PASS · 2 NEUTRAL
Overall verdict✗GrahamFAIL (2/9)✗BuffettFAIL (0/9)✗LynchFAIL (3/7)✗GreenblattRank #2795✓PiotroskiPASS (F-Score 4)✗DremanFAIL (3/11)✗MungerFAIL (0/4)✗PabraiFAIL (0/3)✗AkreFAIL (1/6)✗MarksFAIL (0/5)✓AckmanPASS (5/9)✗TempletonFAIL (3/8)✗SleepFAIL (2/6)•AsnessNEUTRAL (Not ranked)✗NeffFAIL (2/6)✗SchlossFAIL (2/7)•OshaughnessyNEUTRAL (Not ranked) - Cash Flow20% pass✓ 3✗ 9▾
8 of 10 flag TARS's cash flow — Buffett, Piotroski, Dreman +5 more
Free Cash Flow Proxy$-13.8M✗BuffettPositive and growingFCF Positive and Growing$32.4M✓LynchPositive and growingOperating Cash Flow$-12.5M✗PiotroskiCFO > 0(CFO / Total Assets) vs ROACFO/Assets=-2.21%, ROA=-11.81%✓PiotroskiCFO/Assets > ROAPrice / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xP/E or FCF YieldFCF Yield=-0.6%✗PabraiP/E < 15 or FCF Yield > 10%FCF Positive1/7 years FCF positive✗MarksPositive FCF in majority of recent years(OCF - CapEx) / Market Cap0.9%✗Ackman>= 4%Price / FCF per ShareN/A (negative FCF)✗Ackman<= 25Positive Operating Cash Flow frequency1/7 years positive✗SleepPositive OCF in >= 70% of available yearsOperating Cash Flow - Capital Expenditures$32.4M✓Neff> $0 (app proxy for a strong fundamental case)(Operating cash flow - capex) / market capitalization+0.82%; #2426/4519 (top 53.7%)✗OshaughnessyTop 10% of eligible cross-section - Debt & Leverage50% pass✓ 9✗ 6▾
6 of 12 pass — Buffett, Lynch, Munger +3 more object
LT Debt vs Net Current AssetsLT Debt $72.9M vs NCA $218.3M✓GrahamLT Debt <= Net Current AssetsDebt/Equity & Interest CoverageD/E: 0.70, IC: -80.2x✗BuffettD/E < 0.5 AND Interest Coverage > 5xTotal Debt / Equity0.70✗Lynch< 0.33Cash - Long-term Debt$63.6M✓LynchPositive preferredLT Debt / Total Assets Change19.06% -> 12.89%✓PiotroskiDecreased YoYCurrent Assets / Current Liabilities1.96✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)Total Debt / Shareholders' Equity0.70✓Dreman< 0.8✓Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✓SchlossD/E < 1.00xDebt Levels0.70✗MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3Interest Coverage & Debt/EBITDAIC=-7.9x, D/EBITDA=N/A (D&A unavailable)✗MarksInterest Coverage > 3x; Debt/EBITDA < 4xTotal Debt / Shareholders Equity0.70✓Ackman<= 1.0Negative debt-to-equity (higher means less debt)-0.7011; #2841/4210 (top 67.5%)✗AsnessTop 30% of eligible cross-section
Business & financials
Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.
Company Profile
Financial Snapshot
Shareholder Return
Fiscal 2025
Issued 10.9% of shares last year, 24.4% issued over two.
- Buybacks
- —
- Dividends
- —
Company Financials
Latest TTM and quarters alongside annual years
TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.
The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.
| Metric | TTM · 2026-09-30 2025-10-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: revenue, net income, operating income, ebit, interest expense, operating cash flow, capex. | Q3 FY 2026 2026-07-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, capex. | Q2 FY 2026 2026-04-01 – 2026-06-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, capex. | Q1 FY 2026 2026-01-01 – 2026-03-31 Sources | FY 2025Sources
| FY 2024Sources
| FY 2023Sources
| FY 2022Sources
| FY 2021Sources
|
|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $4.0Bcurrent | -- | -- | -- | $2.7Best. | $2.1Best. | $932.1Mest. | $421.3Mest. | $415.6Mest. |
| Revenue | $682.2M↑86% | $194.6M↑64% | $173.9M↑69% | $162.1M↑107% | $451.4M↑147% | $183.0M↑949% | $17.4M↓32% | $25.8M↓55% | $57.0M |
| Operating Income | -$696.1M↓696% | -$662.1M↓4457% | -$19.9M↑10% | -$6.1M↑77% | -$71.0M↑41% | -$120.6M↑16% | -$143.2M↓128% | -$62.7M↓416% | -$12.2M |
| Net Income | -$702.2M↓765% | -$668.3M↓5211% | -$18.6M↑9% | -$7.0M↑72% | -$66.4M↑43% | -$115.6M↑15% | -$135.9M↓119% | -$62.1M↓349% | -$13.8M |
| EPS (Diluted) | -- | $-14.40↓4700% | $-0.43↑10% | $-0.16↑75% | $-1.59↑48% | $-3.07↑34% | $-4.62↓83% | $-2.52↓276% | $-0.67 |
| Gross Margin | — | — | — | — | — | — | — | — | — |
| Operating Margin | -102.0%↓327% | -340.3%↓2680% | -11.4%↑47% | -3.8%↑89% | -15.7%↑76% | -65.9%↑92% | -820.5%↓238% | -242.9%↓1040% | -21.3% |
| ROE | -675.0%↓2687% | — | — | — | -19.3%↑62% | -51.5%↑25% | -69.0%↓114% | -32.2%↓288% | -8.3% |
| Total Debt | $72.9M↑1% | $72.9M↑1% | $72.8M↑1% | $72.6M↑1% | $72.4M↑1% | $71.8M↑141% | $29.8M↑53% | $19.4M | $0 |
| Shareholders' Equity | $104.0M↓69% | $104.0M↓69% | $346.7M↑4% | $349.0M↑2% | $343.4M↑53% | $224.5M↑14% | $197.0M↑2% | $192.9M↑16% | $166.7M |
| Current Ratio | 1.96↓54% | 1.96↓54% | 3.20↓39% | 3.74↓33% | 3.85↓13% | 4.42↓36% | 6.93↓53% | 14.61↓5% | 15.33 |
| Debt / Equity | 0.70↑225% | 0.70↑225% | 0.21↓3% | 0.21↓1% | 0.21↓34% | 0.32↑111% | 0.15↑50% | 0.10 | 0.00 |
| Operating Cash Flow | $49.9M↑192% | -$6.0M↓133% | $61.2M↑308% | -$24.7M↓19% | -$12.5M↑85% | -$83.0M↑29% | -$117.5M↓140% | -$49.0M↓1408% | $3.7M |
| Free Cash Flow | $32.4M↑156% | -$7.2M↓144% | $57.2M↑288% | -$30.5M↓43% | -$22.3M↑74% | -$84.6M↑29% | -$119.0M↓140% | -$49.5M↓1667% | $3.2M |
Score history
Historical Score Timeline
Industry peers
Industry Peers
Similar companies in Pharmaceutical Products
TARS vs Peers — Financial Grading
| Company | Market Cap | Price | Revenue | Net Income | ROE | D/E | Op. Margin | Curr. Ratio | Graham | Buffett | Lynch | Greenblatt | Piotroski | Dreman |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck & Co., Inc.MRK | $364.3B | $147.76 | $65.0B | $18.3B | 34.7% | 0.94 | — | 1.54 | 2/9 | 5/9 | 4/7 | 0/3 | F-Score 4 | 1/11 |
| ABBOTT LABORATORIESABT | $188.0B | $108.52 | $44.3B | $6.5B | 12.5% | 0.25 | 18.2% | 1.58 | 3/9 | 4/9 | 2/7 | 1/3 | F-Score 5 | 3/11 |
| BRISTOL MYERS SQUIBB COBMY | $129.7B | $63.43 | $48.2B | $7.1B | 38.2% | 2.44 | 19.4% | 1.26 | 2/9 | 1/9 | 3/7 | 1/3 | F-Score 8 | 5/11 |
| BIO-TECHNE CorpTECH | $11.4B | $72.80 | $1.2B | $73.4M | 3.8% | — | 8.4% | 3.46 | 4/9 | 3/9 | 3/7 | 0/3 | F-Score 5 | 4/11 |
| REPLIGEN CORPRGEN | $10.7B | $167.79 | $738.3M | $48.9M | 2.3% | 0.26 | 7.5% | 8.37 | 3/9 | 2/9 | 3/7 | 0/3 | F-Score 7 | 5/11 |
| IONIS PHARMACEUTICALS INCIONS | $4.8B | $29.06 | $943.7M | $381.4M | -78.0% | 3.60 | -40.4% | 3.83 | 3/9 | 1/9 | 1/7 | 0/3 | F-Score 4 | 3/11 |
| NEOGEN CORPNEOG | $2.5B | $11.23 | $870.4M | $7.9M | -0.4% | 0.76 | -2.5% | 3.82 | 3/9 | 1/9 | 2/7 | 0/3 | F-Score 6 | 4/11 |
| Pharvaris N.V.PHVS | $2.4B | $33.36 | — | $206.4M | -64.8% | 0.00 | — | — | 0/9 | 0/9 | 2/7 | 0/3 | F-Score 2 | 2/11 |