Theravance Biopharma, Inc.

TBPH
About the company

Theravance Biopharma, Inc., a biopharmaceutical company, develops and commercializes medicines in the United States. It offers YUPELRI, an once-daily, nebulized long-acting muscarinic antagonist for the treatment of chronic obstructive pulmonary disease (COPD); and Ampreloxetine an investigational, once-daily norepinephrine reuptake inhibitor, Which is in Phase 3 clinical trials for symptomatic neurogenic orthostatic hypotension (nOH) in patients with Multiple System Atrophy (MSA).

Country: United StatesPrice: $17.03Market Cap: $884.2M

Investment snapshot

12%positive consensus
Scored 1d ago

Positive

2

BUY / PASS

Neutral / negative

5 / 9

NEUTRAL / FAIL

Median fair value

$28.78

+69.0% vs price

Models with upside

4 / 17

Positive margin of safety

Strongest signal

8 of 10 pass — Marks and Sleep object

Key risk

11 of 12 flag TBPH's debt & leverage — Graham, Buffett, Lynch +8 more

Framework analysis

VerdictMeaning
BUYPositive purchase signal: the framework's buy requirements are met.
PASSThe company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state.
NEUTRALNeither a positive nor negative conclusion. It does not mean to hold an existing position.
FAILThe company does not clear the framework's requirements.
RankedRanked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL.

Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.

MetricGraham

Defensive Value

Buffett

Quality Compounder

Lynch

GARP

Greenblatt

Magic Formula

Piotroski

F-Score

Dreman

Contrarian Value

Munger

Quality Focus

Pabrai

Dhandho Framework

Akre

Three-Legged Stool

Marks

Risk-Aware Value

Ackman

Activist Value

Templeton

Global Bargain Hunter

Sleep

Scale Economies Shared

Asness

Systematic Factors

Neff

Low-P/E Total Return

Schloss

Asset-Value Discipline

O'Shaughnessy

Systematic Factor Composite

VerdictFAILFAILFAILFAIL · Rank #1854 (Top 59.9%)NEUTRALPASSFAILNEUTRALFAILFAILNEUTRALFAILPASSNEUTRALFAILFAILNEUTRAL
Score
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Intrinsic Value (annual)N/AN/AN/AN/AN/AN/AN/AN/AN/AN/AN/A
Margin of Safety-4.2%+31.0%N/AN/AN/AN/A+77.2%+48.2%N/AN/A+87.3%-34.8%N/AN/AN/AN/AN/A
Financial Basis

TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Annual history · FY 2025

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Market data at 2026-10-01

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Qualitative assessment · Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · TTM ended 2026-06-30 · Market data at 2026-10-01

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Annual history · FY 2025 · Price history 2025-01-01–2026-10-01

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Qualitative assessment

Latest source filing: 2026-03-23

Score computed: 2026-11-14

TTM ended 2026-06-30 · Balance sheet at 2026-06-30 · Price history 2025-01-01–2026-10-01 · Annual history · FY 2025

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Annual history · FY 2025

Latest source filing: 2026-03-23

Score computed: 2026-11-14

Annual history · FY 2025 · Balance sheet at 2026-06-30

Latest source filing: 2026-08-11

Score computed: 2026-11-14

TTM ended 2026-06-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-10-01

Latest source filing: 2026-08-11

Score computed: 2026-11-14

Where It Passes

  • Cash Flow80% pass✓ 10✗ 2▾

    8 of 10 pass — Marks and Sleep object

    Free Cash Flow Proxy$107.5M
    ✓BuffettPositive and growing
    FCF Positive and Growing$238.5M
    ✓LynchPositive and growing
    Operating Cash Flow$238.5M
    ✓PiotroskiCFO > 0
    (CFO / Total Assets) vs ROACFO/Assets=49.13%, ROA=21.81%
    ✓PiotroskiCFO/Assets > ROA
    Price / (CFO / Shares)3.7x
    ✓Dreman< 8x
    P/E or FCF YieldP/E=8.3x, FCF Yield=27.0%
    ✓PabraiP/E < 15 or FCF Yield > 10%
    FCF Positive1/14 years FCF positive
    ✗MarksPositive FCF in majority of recent years
    (OCF - CapEx) / Market Cap27.2%
    ✓Ackman>= 4%
    Price / FCF per Share3.7x
    ✓Ackman<= 25
    Positive Operating Cash Flow frequency1/14 years positive
    ✗SleepPositive OCF in >= 70% of available years
    Operating Cash Flow - Capital Expenditures$238.5M
    ✓Neff> $0 (app proxy for a strong fundamental case)
    (Operating cash flow - capex) / market capitalization+26.97%; #202/4519 (top 4.5%)
    ✓OshaughnessyTop 10% of eligible cross-section
  • Valuation models67% pass✓ 4✗ 2▾

    Models split on TBPH at $17.03 — fair values range $12.63–$133.96

    Graham fair value$16.34
    ✗Graham-4.2% margin vs $17.03
    Buffett fair value$24.67
    ✓Buffett+31.0% margin vs $17.03
    Munger fair value$74.78
    ✓Munger+77.2% margin vs $17.03
    Pabrai fair value$32.88
    ✓Pabrai+48.2% margin vs $17.03
    Ackman fair value$133.96
    ✓Ackman+87.3% margin vs $17.03
    Templeton fair value$12.63
    ✗Templeton-34.8% margin vs $17.03

Where It Falls Short

  • Debt & Leverage8% pass✓ 3✗ 12▾

    11 of 12 flag TBPH's debt & leverage — Graham, Buffett, Lynch +8 more

    LT Debt vs Net Current Assets
    ✗GrahamLT Debt <= Net Current Assets
    Debt/Equity & Interest Coverage
    ✗BuffettD/E < 0.5 AND Interest Coverage > 5x
    Total Debt / Equity
    ✗Lynch< 0.33
    Cash - Long-term Debt
    ✗LynchPositive preferred
    LT Debt / Total Assets Change0.00% -> 0.00%
    ✓PiotroskiDecreased YoY
    Current Assets / Current Liabilities13.54
    ✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)
    Total Debt / Shareholders' Equity
    ✗Dreman< 0.8✗Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✗SchlossD/E < 1.00x
    Debt Levels
    ✗MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3
    Interest Coverage & Debt/EBITDAIC=-1.5x, D/EBITDA=N/A
    ✗MarksInterest Coverage > 3x; Debt/EBITDA < 4x
    Total Debt / Shareholders Equity
    ✗Ackman<= 1.0
    Negative debt-to-equity (higher means less debt)
    ✗AsnessTop 30% of eligible cross-section
  • Verdicts17% pass✓ 2✗ 10▾

    Split decision: 9 FAIL · 5 NEUTRAL · 2 PASS

    Overall verdict
    ✗GrahamFAIL (2/9)✗BuffettFAIL (2/9)✗LynchFAIL (3/7)✗GreenblattRank #1854•PiotroskiNEUTRAL (F-Score 7)✓DremanPASS (6/11)✗MungerFAIL (1/4)•PabraiNEUTRAL (2/3)✗AkreFAIL (1/6)✗MarksFAIL (1/5)•AckmanNEUTRAL (6/9)✗TempletonFAIL (3/8)✓SleepPASS (3/6)•AsnessNEUTRAL (Not ranked)✗NeffFAIL (3/6)✗SchlossFAIL (1/7)•OshaughnessyNEUTRAL (Not ranked)
  • Profitability19% pass✓ 14✗ 21▾

    13 of 16 flag TBPH's profitability — Graham, Buffett, Lynch +10 more

    Net income / market capitalization+6.09%; #1395/6340 (top 22.0%)
    ✓AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-section
    Positive EPS (10 years)2/15 years positive
    ✗GrahamPositive EPS every year for 10 years
    EPS Growth (3-yr avg, 10-yr window)N/A (negative base EPS)
    ✗Graham>= 33% growth
    Net Income Positive (10+ years)2/15 years positive
    ✗BuffettPositive every year for 10+ years
    ROE (up to 5-year arithmetic mean)-14.6%
    ✗Buffett> 15% arithmetic mean (app rule)
    Operating Margin (10-yr trend)-3.4% (latest)
    ✓BuffettStable or rising over 10 years
    Free Cash Flow Proxy$107.5M
    ✓BuffettPositive and growing
    Earnings Variance (10-yr CoV)N/A (negative mean EPS)
    ✗BuffettCoV < 0.3
    Retained Earnings Effectiveness
    ✗Buffett$1 retained -> > $1 market value created
    Basic earnings-growth PEG (dividends excluded)P/E 8.3x (growth N/A)
    ✗Lynch< 1.0 (ideally < 0.5)
    3-5 Year EPS CAGR-44.2%
    ✗Lynch15-30% (Fast Grower); > 0% to pass
    ROE18.6%
    ✓Lynch> 15%
    EBIT / Enterprise Value-0.5%
    ✗Greenblatt> 10%
    Earnings Yield + ROC AssessmentEY=-0.5%, ROC=-1.7%
    ✗GreenblattBoth EY > 10% and ROC > 25%
    Net Income / Total Assets21.81%
    ✓PiotroskiROA > 0
    ROA Change YoY-15.93% -> 21.81% (delta: +37.74%)
    ✓PiotroskiCurrent ROA > Prior ROA
    (CFO / Total Assets) vs ROACFO/Assets=49.13%, ROA=21.81%
    ✓PiotroskiCFO/Assets > ROA
    Gross Margin Change YoY
    ✗PiotroskiImproved YoY
    Pre-Tax Income / Revenue56.5%
    ✓Dreman>= 8%
    Net Income / Shareholders' Equity18.6%
    ✓Dreman> 12%
    Margin of SafetyP/E=8.3x, P/B=3.0x
    ✓PabraiP/B < 1.5 or P/E < 15
    Return on Equity-7.5% (3-yr avg)
    ✗AkreROE > 20% (3-year avg)
    Discount to Intrinsic ValueN/A (negative normalized EPS)
    ✗Marks>= 20% below intrinsic value
    Positive Net Income Frequency2/14 years positive
    ✗MarksPositive net income in >= 7 of last 10 years
    Operating Income / Revenue-4.0%
    ✗Ackman>= 15%
    Net Income / Shareholders Equity18.6%
    ✓Ackman>= 15%
    5-Year EPS CAGR
    ✗Templeton> 0% (5-year EPS CAGR)
    Operating Margin Trend-97.6% (2023) -> -3.4% (2025)
    ✓TempletonNon-negative operating-margin trend over 3 years
    Revenue growth vs. gross and operating margin trendrevenue up, operating margin -97.6% -> -3.4%
    ✓SleepRevenue rising; gross margin flat or falling; operating margin holding
    Gross profit / total assets
    ✗AsnessTop 30% of eligible cross-section
    Net income / positive book equity+18.57%; #875/5226 (top 16.7%)
    ✓AsnessTop 30% of eligible cross-section
    Negative 5-year standard deviation of ROA-0.6789; #5114/5884 (top 86.9%)
    ✗AsnessTop 30% of eligible cross-section
    3-5 Year Diluted EPS CAGR-44.2% over 3 years
    ✗Neff7%-20% annualized
    Positive Diluted-EPS Years2/10 years positive
    ✗Schloss>= 70% positive over 5-10 observed years (app rule)
  • Valuation23% pass✓ 10✗ 18▾

    10 of 13 flag TBPH's valuation — Graham, Lynch, Greenblatt +7 more

    Net income / market capitalization+6.09%; #1395/6340 (top 22.0%)
    ✓AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-section
    Price / 3-yr avg EPS
    ✗Graham<= 15x
    Price-to-Book Ratio3.0x
    ✗Graham<= 1.5x
    P/E x P/B
    ✗Graham<= 22.5
    Basic earnings-growth PEG (dividends excluded)P/E 8.3x (growth N/A)
    ✗Lynch< 1.0 (ideally < 0.5)
    EBIT / Enterprise Value-0.5%
    ✗Greenblatt> 10%
    Earnings Yield + ROC AssessmentEY=-0.5%, ROC=-1.7%
    ✗GreenblattBoth EY > 10% and ROC > 25%
    Price / EPS8.3x
    ✓Dreman< 12x✓Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)
    Price / (CFO / Shares)3.7x
    ✓Dreman< 8x
    Price / Book Value per Share3.0x
    ✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)
    Valuation ReasonablenessP/E=8.3x, OE Yield=12.3%
    ✓MungerP/E < 25 or Owner Earnings Yield > 5%
    P/E or FCF YieldP/E=8.3x, FCF Yield=27.0%
    ✓PabraiP/E < 15 or FCF Yield > 10%
    P/B or P/E vs. Historical AverageP/E=8.3x, P/B=3.0x
    ✓MarksP/E < 15 or P/B < 2.0
    Discount to Intrinsic ValueN/A (negative normalized EPS)
    ✗Marks>= 20% below intrinsic value
    Price / FCF per Share3.7x
    ✓Ackman<= 25
    Price vs. Trailing Low191% of trailing low ($8.93)
    ✗Templeton<= 120% of trailing low (certified split-adjusted live window)
    Positive book equity / market capitalization+0.3277; #3570/6449 (top 55.4%)
    ✗AsnessTop 30% of eligible cross-section
    Price / Diluted EPS8.3x
    ✓NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)
    (EPS CAGR % + Dividend Yield %) / P/E
    ✗Neff> 0.7 (Neff's published traditional edge)
    Price / Tangible Book Value per Share2.96x
    ✗SchlossP/TBV <= 1.00x (app cutoff)
    Book Value per Share Change
    ✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)
    Revenue / market capitalization+0.1180; #4238/5247 (top 80.8%)
    ✗OshaughnessyTop 10% of eligible cross-section
    (Operating cash flow - capex) / market capitalization+26.97%; #202/4519 (top 4.5%)
    ✓OshaughnessyTop 10% of eligible cross-section
    Trailing six-month price return through the evaluation date+1.73%; #2473/6202 (top 39.9%)
    ✗OshaughnessyTop 10% of eligible cross-section
  • Growth25% pass✓ 6✗ 7▾

    6 of 8 flag TBPH's growth — Graham, Lynch, Dreman +3 more

    EPS Growth (3-yr avg, 10-yr window)N/A (negative base EPS)
    ✗Graham>= 33% growth
    Basic earnings-growth PEG (dividends excluded)P/E 8.3x (growth N/A)
    ✗Lynch< 1.0 (ideally < 0.5)
    3-5 Year EPS CAGR-44.2%
    ✗Lynch15-30% (Fast Grower); > 0% to pass
    Inventory Growth vs Revenue GrowthN/A (no inventory)
    ✓LynchInventory growth < Revenue growth
    EPS Growth Direction$-0.30 (2012) -> $2.06 (2025)
    ✓DremanPositive over recent years
    EPS CAGR
    ✗Dreman> 5% annualized
    Positive Net Income Frequency2/14 years positive
    ✗MarksPositive net income in >= 7 of last 10 years
    3yr Median Revenue Growth12.1%
    ✓Ackman>= 5%
    Positive EPS Growth Frequency3/5 years with positive EPS growth
    ✓AckmanPositive EPS growth in >= 3 of last 5 years
    5-Year EPS CAGR
    ✗Templeton> 0% (5-year EPS CAGR)
    Revenue growth vs. gross and operating margin trendrevenue up, operating margin -97.6% -> -3.4%
    ✓SleepRevenue rising; gross margin flat or falling; operating margin holding
    5-year Revenue CAGR8.4%
    ✓SleepCAGR > 7%
    3-5 Year Diluted EPS CAGR-44.2% over 3 years
    ✗Neff7%-20% annualized
  • Efficiency38% pass✓ 4✗ 7▾

    5 of 8 flag TBPH's efficiency — Buffett, Greenblatt, Munger +2 more

    Current Ratio13.54
    ✓Graham>= 2.0
    ROIC (3-5 yr avg)-222.3%
    ✗Buffett> 10%
    ROIC - WACC-232.3%
    ✗BuffettPositive (WACC = 10%)
    EBIT / (NWC + Net Fixed Assets)-1.7%
    ✗Greenblatt> 25%
    Current Ratio Change YoY5.02 -> 10.93
    ✓PiotroskiIncreased YoY
    Revenue / Total Assets Change YoY0.18x -> 0.22x
    ✓PiotroskiImproved YoY
    Current Assets / Current Liabilities13.54
    ✓Dreman> 1.5
    Return on Invested Capital
    ✗Munger> 15%
    ROIC (high and growing)FY2023: ROIC=-20.8%; FY2024: ROIC=unavailable; FY2025: ROIC=unavailable
    ✗AkreLatest 3 consecutive FYs: ROIC > 15% in each
    Reinvestment Rate x ROIC
    ✗AkreReinvestment Rate * ROIC > 10%
    ROIC (5-year)0/2 years above 12% (latest -20.8%)
    ✗SleepROIC > 12% in a majority of years

Business & financials

Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.

Company Profile

Industry: Pharmaceutical Products
SIC Sector: Chemicals & Pharmaceuticals
Size: Small Cap($884.2M)
Revenue: $107.5M+66.9% YoY
Net Income: $105.9M+287.7% YoY

Financial Snapshot

Operating Margin-3.4%
Return on Equity35.7%
Debt / Equity--
Current Ratio10.93
EPS (Diluted)$2.06
Shares Retired−4.1% / −6.9% 2y

Shareholder Return

Fiscal 2025

Issued 4.1% of shares last year, 6.9% issued over two.

Buybacks
—
Dividends
—

Company Financials

Latest TTM and quarters alongside annual years

TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.

The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.

MetricTTM · 2026-06-30

2025-07-01 – 2026-06-30

Sources · derived quarter values

Derived from cumulative filings: operating cash flow, capex, pre tax income, interest expense.

Q2 FY 2026

2026-04-01 – 2026-06-30

Sources · derived quarter values

Derived from cumulative filings: operating cash flow.

Q1 FY 2026

2026-01-01 – 2026-03-31

Sources
FY 2025
Sources
  • 10-K · 2026-03-23
FY 2024
Sources
  • 10-K · 2025-03-07
FY 2023
Sources
  • 10-K · 2024-03-01
FY 2022
Sources
  • 10-K · 2023-03-01
FY 2021
Sources
  • 10-K · 2022-02-28
Market Cap$884.2Mcurrent----$975.3Mest.$464.0Mest.$456.6Mest.$679.6Mest.$680.5Mest.
Revenue$104.3M↑35%$20.7M↓21%$17.7M↑15%$107.5M↑67%$64.4M↑12%$57.4M↑12%$51.3M↓7%$55.3M
Operating Income-$4.2M↑89%-$8.3M↓204%-$9.5M↑34%-$3.6M↑92%-$46.9M↑16%-$56.0M↑39%-$92.0M↑64%-$257.8M
Net Income$53.8M↑313%-$5.9M↓111%-$4.9M↑64%$105.9M↑288%-$56.4M↓2%-$55.2M↓106%$872.1M↑537%-$199.4M
EPS (Diluted)--$-0.11↓110%$-0.10↑63%$2.06↑279%$-1.15↓15%$-1.00↓108%$11.85↑513%$-2.87
Gross Margin————————
Operating Margin-4.0%↑92%-39.9%↓284%-53.6%↑43%-3.4%↑95%-72.9%↑25%-97.6%↑46%-179.1%↑62%-466.1%
ROE18.6%↑220%——35.7%↑211%-32.1%↓24%-25.9%↓113%197.4%↑235%58.9%
Total Debt----------$0--$616.3M
Shareholders' Equity$289.7M↑29%$289.7M↑29%$290.6M↑75%$296.7M↑69%$175.5M↓18%$213.0M↓52%$441.8M↑230%-$338.6M
Current Ratio13.54↑102%13.54↑102%13.14↑176%10.93↑118%5.02↓7%5.39↓56%12.31↑189%4.26
Debt / Equity—————0.00—-1.82
Operating Cash Flow$53.7M↓78%-$7.0M↓103%$73.3M↑70%$238.5M↑2168%-$11.5M↑57%-$27.0M↑86%-$187.0M↑10%-$207.9M
Free Cash Flow------$238.5M↑2110%-$11.9M↑60%-$29.5M↑84%-$187.6M↑11%-$211.3M

Score history

Historical Score Timeline

Industry peers

Industry Peers

Similar companies in Pharmaceutical Products

TBPH vs Peers — Financial Grading

Revenue$107.5MBottom 25%
Net Income$105.9MMedian
ROE35.7%Top 25%
D/E—
Op. Margin-3.4%Bottom 25%
Curr. Ratio10.93Top 25%
CompanyMarket CapPriceRevenueNet IncomeROED/EOp. MarginCurr. RatioGrahamBuffettLynchGreenblattPiotroskiDreman
Merck & Co., Inc.MRK$364.3B$147.76$65.0B$18.3B34.7%0.94—1.542/95/94/70/3F-Score 41/11
ABBOTT LABORATORIESABT$188.0B$108.52$44.3B$6.5B12.5%0.2518.2%1.583/94/92/71/3F-Score 53/11
BRISTOL MYERS SQUIBB COBMY$129.7B$63.43$48.2B$7.1B38.2%2.4419.4%1.262/91/93/71/3F-Score 85/11
BIO-TECHNE CorpTECH$11.4B$72.80$1.2B$73.4M3.8%—8.4%3.464/93/93/70/3F-Score 54/11
REPLIGEN CORPRGEN$10.7B$167.79$738.3M$48.9M2.3%0.267.5%8.373/92/93/70/3F-Score 75/11
IONIS PHARMACEUTICALS INCIONS$4.8B$29.06$943.7M$381.4M-78.0%3.60-40.4%3.833/91/91/70/3F-Score 43/11
NEOGEN CORPNEOG$2.5B$11.23$870.4M$7.9M-0.4%0.76-2.5%3.823/91/92/70/3F-Score 64/11
Pharvaris N.V.PHVS$2.4B$33.36—$206.4M-64.8%0.00——0/90/92/70/3F-Score 22/11