Zai Lab Ltd
ZLABAbout the company
Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases.
Investment snapshot
Positive
3
BUY / PASS
Neutral / negative
1 / 12
NEUTRAL / FAIL
Median fair value
—
No comparable estimates
Models with upside
0 / 17
Positive margin of safety
Key risk
All 13 investors flag ZLAB's valuation
Framework analysis
| Verdict | Meaning |
|---|---|
| BUY | Positive purchase signal: the framework's buy requirements are met. |
| PASS | The company clears the framework's checklist or screen, but the framework does not produce a buy signal. For valuation frameworks this often means margin of safety is missing, insufficient, or unavailable; some screen-only frameworks have no intrinsic-value BUY state. |
| NEUTRAL | Neither a positive nor negative conclusion. It does not mean to hold an existing position. |
| FAIL | The company does not clear the framework's requirements. |
| Ranked | Ranked strategies do not use PASS: selected cohort is BUY, outside the cohort is FAIL, and unranked is NEUTRAL. |
Current investor scores use trailing 12-month flows and the latest balance sheet where supported. Multi-year and EPS tests retain annual history; each framework shows its financial basis below. Intrinsic values use annual financials.
| Metric | Graham Defensive Value | Buffett Quality Compounder | Lynch GARP | Greenblatt Magic Formula | Piotroski F-Score | Dreman Contrarian Value | Munger Quality Focus | Pabrai Dhandho Framework | Akre Three-Legged Stool | Marks Risk-Aware Value | Ackman Activist Value | Templeton Global Bargain Hunter | Sleep Scale Economies Shared | Asness Systematic Factors | Neff Low-P/E Total Return | Schloss Asset-Value Discipline | O'Shaughnessy Systematic Factor Composite |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Verdict | FAIL | FAIL | FAIL | Not ranked | PASS | FAIL | FAIL | FAIL | FAIL | FAIL | PASS | FAIL | PASS | FAIL | FAIL | FAIL | NEUTRAL |
| Score | |||||||||||||||||
| Analysis | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… | Checking access… |
| Intrinsic Value (annual) | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Margin of Safety | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Financial Basis | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Annual history · FY 2025 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 · TTM ended 2026-09-30 vs 2025-09-30 · TTM ended 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Qualitative assessment · Annual history · FY 2025 Latest source filing: 2026-02-26 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Qualitative assessment Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Market data at 2026-11-01 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · Qualitative assessment Latest source filing: 2026-02-26 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Balance sheet at 2026-09-30 · Price history 2025-01-01–2026-11-01 · Annual history · FY 2025 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · TTM ended 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | Annual history · FY 2025 · Balance sheet at 2026-09-30 Latest source filing: 2026-11-05 Score computed: 2026-11-14 | TTM ended 2026-09-30 · Annual history · FY 2025 · Price history 2025-01-01–2026-11-01 Latest source filing: 2026-11-05 Score computed: 2026-11-14 |
Where It Passes
Where It Falls Short
- Valuation0% pass✗ 28▾
All 13 investors flag ZLAB's valuation
Price / 3-yr avg EPS✗Graham<= 15xPrice-to-Book Ratio3.8x✗Graham<= 1.5xP/E x P/B✗Graham<= 22.5Basic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)EBIT / Enterprise Value-8.8%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-8.8%, ROC=N/A (invested capital <= 0)✗GreenblattBoth EY > 10% and ROC > 25%Price / EPS✗Dreman< 12x✗Templeton< 12x (fixed ceiling; proxy for the market's cheapest 40%)Price / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xPrice / Book Value per Share3.8x✗Dreman< 1.2x✗Templeton< 1.5x✗SchlossP/B <= 0.80x (app cutoff)Valuation ReasonablenessOE Yield=-6.2%✗MungerP/E < 25 or Owner Earnings Yield > 5%P/E or FCF YieldFCF Yield=-5.2%✗PabraiP/E < 15 or FCF Yield > 10%P/B or P/E vs. Historical AverageP/B=3.8x✗MarksP/E < 15 or P/B < 2.0Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePrice / FCF per ShareN/A (negative FCF)✗Ackman<= 25Price vs. Trailing Low148% of trailing low ($1.66)✗Templeton<= 120% of trailing low (certified split-adjusted live window)Net income / market capitalization-6.46%; #3977/6340 (top 62.7%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionPositive book equity / market capitalization+0.1834; #4264/6449 (top 66.1%)✗AsnessTop 30% of eligible cross-sectionPrice / Diluted EPS✗NeffP/E <= 15x (app proxy for a P/E 40%-60% below the market)(EPS CAGR % + Dividend Yield %) / P/E✗Neff> 0.7 (Neff's published traditional edge)Price / Tangible Book Value per Share4.23x✗SchlossP/TBV <= 1.00x (app cutoff)Book Value per Share Change-56.8%✗SchlossLatest BVPS >= earliest BVPS over >= 3 years (app rule)Revenue / market capitalization+0.1438; #4095/5247 (top 78.0%)✗OshaughnessyTop 10% of eligible cross-section(Operating cash flow - capex) / market capitalization-5.32%; #3001/4519 (top 66.4%)✗OshaughnessyTop 10% of eligible cross-sectionTrailing six-month price return through the evaluation date+13.68%; #1660/6202 (top 26.8%)✗OshaughnessyTop 10% of eligible cross-section - Cash Flow0% pass✓ 1✗ 11▾
No clean pass — all 10 investors flag at least one cash flow criterion
Free Cash Flow Proxy$-168.6M✗BuffettPositive and growingFCF Positive and Growing$-163.3M✗LynchPositive and growingOperating Cash Flow$-150.8M✗PiotroskiCFO > 0(CFO / Total Assets) vs ROACFO/Assets=-12.86%, ROA=-14.97%✓PiotroskiCFO/Assets > ROAPrice / (CFO / Shares)N/A (negative CFPS)✗Dreman< 8xP/E or FCF YieldFCF Yield=-5.2%✗PabraiP/E < 15 or FCF Yield > 10%FCF Positive0/11 years FCF positive✗MarksPositive FCF in majority of recent years(OCF - CapEx) / Market Cap-6.0%✗Ackman>= 4%Price / FCF per ShareN/A (negative FCF)✗Ackman<= 25Positive Operating Cash Flow frequency0/11 years positive✗SleepPositive OCF in >= 70% of available yearsOperating Cash Flow - Capital Expenditures$-163.3M✗Neff> $0 (app proxy for a strong fundamental case)(Operating cash flow - capex) / market capitalization-5.32%; #3001/4519 (top 66.4%)✗OshaughnessyTop 10% of eligible cross-section - Profitability6% pass✓ 5✗ 30▾
15 of 16 flag ZLAB's profitability — Graham, Buffett, Lynch +12 more
Positive EPS (10 years)0/12 years positive✗GrahamPositive EPS every year for 10 yearsEPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthNet Income Positive (10+ years)0/12 years positive✗BuffettPositive every year for 10+ yearsROE (up to 5-year arithmetic mean)-38.1%✗Buffett> 15% arithmetic mean (app rule)Operating Margin (10-yr trend)-49.9% (latest)✓BuffettStable or rising over 10 yearsFree Cash Flow Proxy$-168.6M✗BuffettPositive and growingEarnings Variance (10-yr CoV)✗BuffettCoV < 0.3Retained Earnings Effectiveness✗Buffett$1 retained -> > $1 market value createdBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passROE-35.2%✗Lynch> 15%EBIT / Enterprise Value-8.8%✗Greenblatt> 10%Earnings Yield + ROC AssessmentEY=-8.8%, ROC=N/A (invested capital <= 0)✗GreenblattBoth EY > 10% and ROC > 25%Net Income / Total Assets-14.97%✗PiotroskiROA > 0ROA Change YoY-21.68% -> -14.97% (delta: +6.71%)✓PiotroskiCurrent ROA > Prior ROA(CFO / Total Assets) vs ROACFO/Assets=-12.86%, ROA=-14.97%✓PiotroskiCFO/Assets > ROAGross Margin Change YoY63.1% -> 58.6%✗PiotroskiImproved YoYPre-Tax Income / Revenue-45.9%✗Dreman>= 8%Net Income / Shareholders' Equity-35.2%✗Dreman> 12%Margin of SafetyP/B=3.8x✗PabraiP/B < 1.5 or P/E < 15Return on Equity-32.4% (3-yr avg)✗AkreROE > 20% (3-year avg)Discount to Intrinsic ValueN/A (negative normalized EPS)✗Marks>= 20% below intrinsic valuePositive Net Income Frequency0/11 years positive✗MarksPositive net income in >= 7 of last 10 yearsOperating Income / Revenue-63.0%✗Ackman>= 15%Net Income / Shareholders Equity-35.2%✗Ackman>= 15%5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Operating Margin Trend-137.4% (2023) -> -49.9% (2025)✓TempletonNon-negative operating-margin trend over 3 yearsRevenue growth vs. gross and operating margin trendgross margin 64.1% -> 58.6%, operating margin -137.4% -> -49.9%✓SleepRevenue rising; gross margin flat or falling; operating margin holdingNet income / market capitalization-6.46%; #3977/6340 (top 62.7%)✗AsnessTop 30% of eligible cross-section✗OshaughnessyTop 10% of eligible cross-sectionGross profit / total assets+23.00%; #1852/3702 (top 50.0%)✗AsnessTop 30% of eligible cross-sectionNet income / positive book equity-35.22%; #3998/5226 (top 76.5%)✗AsnessTop 30% of eligible cross-sectionNegative 5-year standard deviation of ROA-0.1029; #3518/5884 (top 59.8%)✗AsnessTop 30% of eligible cross-section3-5 Year Diluted EPS CAGR✗Neff7%-20% annualizedPositive Diluted-EPS Years0/10 years positive✗Schloss>= 70% positive over 5-10 observed years (app rule) - Verdicts20% pass✓ 3✗ 12▾
Split decision: 12 FAIL · 3 PASS · 1 NEUTRAL
Overall verdict✗GrahamFAIL (2/9)✗BuffettFAIL (1/9)✗LynchFAIL (0/7)•GreenblattNot ranked✓PiotroskiPASS (F-Score 4)✗DremanFAIL (3/11)✗MungerFAIL (1/4)✗PabraiFAIL (0/3)✗AkreFAIL (1/6)✗MarksFAIL (0/5)✓AckmanPASS (5/9)✗TempletonFAIL (3/8)✓SleepPASS (3/6)✗AsnessFAIL (Rank #1831/2370 (Top 77.3%))✗NeffFAIL (1/6)✗SchlossFAIL (2/7)•OshaughnessyNEUTRAL (Not ranked) - Growth25% pass✓ 4✗ 9▾
6 of 8 flag ZLAB's growth — Graham, Lynch, Dreman +3 more
EPS Growth (3-yr avg, 10-yr window)✗Graham>= 33% growthBasic earnings-growth PEG (dividends excluded)✗Lynch< 1.0 (ideally < 0.5)3-5 Year EPS CAGR✗Lynch15-30% (Fast Grower); > 0% to passInventory Growth vs Revenue GrowthInv: 27.0% vs Rev: 0.0%✗LynchInventory growth < Revenue growthEPS Growth Direction✗DremanPositive over recent yearsEPS CAGR✗Dreman> 5% annualizedPositive Net Income Frequency0/11 years positive✗MarksPositive net income in >= 7 of last 10 years3yr Median Revenue Growth24.0%✓Ackman>= 5%Positive EPS Growth Frequency4/5 years with positive EPS growth✓AckmanPositive EPS growth in >= 3 of last 5 years5-Year EPS CAGR✗Templeton> 0% (5-year EPS CAGR)Revenue growth vs. gross and operating margin trendgross margin 64.1% -> 58.6%, operating margin -137.4% -> -49.9%✓SleepRevenue rising; gross margin flat or falling; operating margin holding5-year Revenue CAGR56.5%✓SleepCAGR > 7%3-5 Year Diluted EPS CAGR✗Neff7%-20% annualized - Efficiency25% pass✓ 3✗ 8▾
6 of 8 flag ZLAB's efficiency — Buffett, Greenblatt, Piotroski +3 more
Current Ratio2.04✓Graham>= 2.0ROIC (3-5 yr avg)-1020.4%✗Buffett> 10%ROIC - WACC-1030.4%✗BuffettPositive (WACC = 10%)EBIT / (NWC + Net Fixed Assets)N/A (invested capital <= 0)✗Greenblatt> 25%Current Ratio Change YoY3.51 -> 2.45✗PiotroskiIncreased YoYRevenue / Total Assets Change YoY0.34x -> 0.39x✓PiotroskiImproved YoYCurrent Assets / Current Liabilities2.04✓Dreman> 1.5Return on Invested Capital-27.0%✗Munger> 15%ROIC (high and growing)FY2023: ROIC=-36.4%; FY2024: ROIC=-22.9%; FY2025: ROIC=-19.7%✗AkreLatest 3 consecutive FYs: ROIC > 15% in eachReinvestment Rate x ROICN/A (non-positive net income)✗AkreReinvestment Rate * ROIC > 10%ROIC (5-year)0/3 years above 12% (latest -19.7%)✗SleepROIC > 12% in a majority of years - Debt & Leverage50% pass✓ 8✗ 7▾
6 of 12 pass — Graham, Buffett, Lynch +3 more object
Debt Levels0.45✓MungerDebt/Equity < 0.5✗AkreDebt/Equity < 0.3LT Debt vs Net Current Assets✗GrahamLT Debt <= Net Current AssetsDebt/Equity & Interest CoverageD/E: 0.45, IC: -45.2x✗BuffettD/E < 0.5 AND Interest Coverage > 5xTotal Debt / Equity0.45✗Lynch< 0.33Cash - Long-term Debt✗LynchPositive preferredLT Debt / Total Assets Change0.00% -> 0.00%✓PiotroskiDecreased YoYCurrent Assets / Current Liabilities2.04✓Dreman> 1.5✓SchlossCurrent ratio >= 1.50x (app cutoff)Total Debt / Shareholders' Equity0.45✓Dreman< 0.8✓Templeton< 1.0 (fixed cap; proxy for below-sector-median leverage)✓SchlossD/E < 1.00xInterest Coverage & Debt/EBITDAIC=-45.2x, D/EBITDA=N/A✗MarksInterest Coverage > 3x; Debt/EBITDA < 4xTotal Debt / Shareholders Equity0.45✓Ackman<= 1.0Negative debt-to-equity (higher means less debt)-0.4480; #2360/4210 (top 56.1%)✗AsnessTop 30% of eligible cross-section
Business & financials
Financial snapshot: annual FY 2025. Current investor scores may use newer quarterly data.
Company Profile
Financial Snapshot
Shareholder Return
Fiscal 2025
Issued 2.4% of shares last year, 13.6% issued over two.
- Buybacks
- —
- Dividends
- —
Company Financials
Latest TTM and quarters alongside annual years
TTM sums four consecutive quarters and uses the latest quarter-end balances. Quarter columns show three-month results; annual columns show full-year totals. Growth compares the same period a year earlier. EPS is not added for TTM; full-year ratios are blank for quarters.
The latest annual period end is unavailable. Showing the latest fiscal cycle’s quarters; quarter and annual columns may overlap. Quarterly shows the full quarter history.
| Metric | TTM · 2026-09-30 2025-10-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: revenue, net income, operating income, ebit, pre tax income, interest expense, operating cash flow, depreciation amortization, capex. | Q3 FY 2026 2026-07-01 – 2026-09-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, depreciation amortization, capex. | Q2 FY 2026 2026-04-01 – 2026-06-30 Sources · derived quarter valuesDerived from cumulative filings: operating cash flow, depreciation amortization, capex. | Q1 FY 2026 2026-01-01 – 2026-03-31 Sources | FY 2025Sources
| FY 2024Sources
| FY 2023Sources
| FY 2022Sources
| FY 2021Sources
|
|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $3.1Bcurrent | -- | -- | -- | $18.2Best. | $29.2Best. | $20.9Best. | $40.4Best. | $47.4Best. |
| Revenue | $441.7M | $108.2M↓7% | $106.3M↓3% | $99.6M↓6% | $460.2M↑15% | $399.0M↑50% | $266.7M↑24% | $215.0M↑49% | $144.3M |
| Operating Income | -$278.3M↓22% | -$63.0M↓29% | -$76.5M↓39% | -$69.4M↓23% | -$229.4M↑19% | -$282.1M↑23% | -$366.6M↑9% | -$404.4M↑42% | -$700.1M |
| Net Income | -$198.4M↑4% | -$46.1M↓28% | -$50.8M↓25% | -$51.0M↓5% | -$175.5M↑32% | -$257.1M↑23% | -$334.6M↑25% | -$443.3M↑37% | -$704.5M |
| EPS (Diluted) | -- | $-0.04↓33% | $-0.05↓25% | $-0.05↓25% | $-0.16↑38% | $-0.26↑26% | $-0.35↑24% | $-0.46↑39% | $-0.76 |
| Gross Margin | — | — | — | — | 58.6%↓7% | 63.1%↓1% | 64.1%↓2% | 65.6%↑3% | 63.8% |
| Operating Margin | -63.0%↓22% | -58.2%↓38% | -71.9%↓44% | -69.7%↓32% | -49.9%↑29% | -70.7%↑49% | -137.4%↑27% | -188.0%↑61% | -485.1% |
| ROE | -35.2%↓29% | — | — | — | -24.5%↑20% | -30.6%↑27% | -42.0%↑1% | -42.4%↑17% | -51.1% |
| Total Debt | $252.4M↑24% | $252.4M↑24% | $238.1M↑36% | $213.8M↑23% | $204.5M↑55% | $131.7M | $0 | -- | -- |
| Shareholders' Equity | $563.3M↓26% | $563.3M↓26% | $607.0M↓23% | $662.0M↓18% | $715.5M↓15% | $840.9M↑6% | $796.1M↓24% | $1.0B↓24% | $1.4B |
| Current Ratio | 2.04↓29% | 2.04↓29% | 2.13↓32% | 2.40↓26% | 2.45↓30% | 3.51↓24% | 4.63↓42% | 8.04↑3% | 7.78 |
| Debt / Equity | 0.45↑68% | 0.45↑68% | 0.39↑78% | 0.32↑51% | 0.29↑83% | 0.16 | 0.00 | — | — |
| Operating Cash Flow | -$159.2M↑12% | -$57.9M↓81% | -$63.4M↓104% | -$11.9M↑81% | -$150.8M↑30% | -$214.9M↓8% | -$198.2M↑46% | -$367.6M↑33% | -$549.2M |
| Free Cash Flow | -$163.3M↑14% | -$58.8M↓68% | -$64.7M↓91% | -$13.1M↑79% | -$158.9M↑28% | -$220.5M↓7% | -$205.4M↑48% | -$392.2M↑31% | -$567.5M |
Score history
Historical Score Timeline
Industry peers
Industry Peers
Similar companies in Pharmaceutical Products
ZLAB vs Peers — Financial Grading
| Company | Market Cap | Price | Revenue | Net Income | ROE | D/E | Op. Margin | Curr. Ratio | Graham | Buffett | Lynch | Greenblatt | Piotroski | Dreman |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Merck & Co., Inc.MRK | $364.3B | $147.76 | $65.0B | $18.3B | 34.7% | 0.94 | — | 1.54 | 2/9 | 5/9 | 4/7 | 0/3 | F-Score 4 | 1/11 |
| ABBOTT LABORATORIESABT | $188.0B | $108.52 | $44.3B | $6.5B | 12.5% | 0.25 | 18.2% | 1.58 | 3/9 | 4/9 | 2/7 | 1/3 | F-Score 5 | 3/11 |
| BRISTOL MYERS SQUIBB COBMY | $129.7B | $63.43 | $48.2B | $7.1B | 38.2% | 2.44 | 19.4% | 1.26 | 2/9 | 1/9 | 3/7 | 1/3 | F-Score 8 | 5/11 |
| BIO-TECHNE CorpTECH | $11.4B | $72.80 | $1.2B | $73.4M | 3.8% | — | 8.4% | 3.46 | 4/9 | 3/9 | 3/7 | 0/3 | F-Score 5 | 4/11 |
| REPLIGEN CORPRGEN | $10.7B | $167.79 | $738.3M | $48.9M | 2.3% | 0.26 | 7.5% | 8.37 | 3/9 | 2/9 | 3/7 | 0/3 | F-Score 7 | 5/11 |
| IONIS PHARMACEUTICALS INCIONS | $4.8B | $29.06 | $943.7M | $381.4M | -78.0% | 3.60 | -40.4% | 3.83 | 3/9 | 1/9 | 1/7 | 0/3 | F-Score 4 | 3/11 |
| NEOGEN CORPNEOG | $2.5B | $11.23 | $870.4M | $7.9M | -0.4% | 0.76 | -2.5% | 3.82 | 3/9 | 1/9 | 2/7 | 0/3 | F-Score 6 | 4/11 |
| Pharvaris N.V.PHVS | $2.4B | $33.36 | — | $206.4M | -64.8% | 0.00 | — | — | 0/9 | 0/9 | 2/7 | 0/3 | F-Score 2 | 2/11 |